Possible

• Steve Kerr and Kris Brown on Leadership, Purpose, and Innovation in Sport and Society

  What does it take to turn tragedy into advocacy, and advocacy into lasting change? This week, Reid and Aria are talking to Warriors head coach Steve Kerr and Kris Brown, president of Brady, the nation’s oldest gun violence prevention organization. Together, they explore how sports, storytelling, and civic engagement can move the needle on one of America’s most polarizing issues: guns. In the first part of this episode, Steve and Kris share the personal and political roots of their partnership. They also dive into the movement for safer gun storage, smart firearm technology, and the bipartisan momentum that’s possible when we lead with empathy over fear. In the second part, the conversation turns to the future of basketball and leadership. Steve reflects on lessons from Phil Jackson and Gregg Popovich, the power of authenticity and collaboration, and how AI, analytics, and even robotics are reshaping the NBA.  For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/  Topics: 01:14 - Hellos and intros 03:28 - Collaboration is the cornerstone of Steve’s leadership philosophy  04:22 - Imposter syndrome, playing under Phil Jackson and Greg Popovich, and coaching Draymond Green  06:02 - Steve’s personal experience with gun violence and using his platform to drive change 07:17 - Lessons Kris learned from working on the Brady Bill  10:43 - Gemini explains the landmark Brady Bill and how it passed 11:48 - Origins of Steve and Brady’s partnership  16:55 - Building bipartisan support for gun violence prevention, like the Bipartisan Safer Communities Act 21:21 - Smart gun technology, gun safes, and other technological solutions 25:27 - “Shut up and dribble” comment and the pushback athletes receive when they speak up 27:29 - Social media as a tool to create cultural change  29:39 - Kris answers the last rapid-fire question and says her goodbyes 32:33 - Midroll 32:38 - Steve digs deeper into Phil Jackson and Greg Popovich’s coaching styles 34:40 - Inspiration v. comparison 35:22 - Hiring staff who bring specific strengths helps form a stronger team 36:21 - Endgame instincts as a coach 39:37 - Helping players navigate modern-age attention and public opinions on social media 42:01 - Internal leadership from players is crucial and Steph Curry as an example 44:33 - How NBA analytics have evolved 46:52 - The Warriors are planning to implement AI-powered robots into their training 47:56 - Players wear monitors that analyze their performance data 49:17 - Discoveries from players’ performance data  50:46 - Analyzing game footage with AI, facial recognition technology, and learning that Steph Curry logs the most miles ran per game in the league 52:56 - Using game footage data to learn opponents’ patterns and build game plans 54:05 - Correlating physical condition and shot success percentage for each player 56:19 - Rapid-fire questions  Select mentions:  Phil Jackson Greg Popovich Brady Bill Uvalde school shooting Bipartisan Safer Communities Act End Family Fire Campaign Maxwell Frost Matthew McConaughey Dan Grunfeld Lopez Twins Maverick: More than a Game by Phil Jackson and Charley Rosen Daryl Morey A Gentleman in Moscow by Amor Towles March for Our Lives Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.

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• Aza Raskin on interspecies communication, empathy, and AI’s next frontier

  Can AI help us better understand animals and, if it could, what might we discover? This week’s episode was recorded live at the 2025 Masters of Scale Summit where Reid and Aria sat down with Aza Raskin, co-founder and CEO of the Earth Species Project. Aza and his team are using AI to decode the languages and cultures of non-human species. From dolphins that invent new tricks together to crows that raise each other’s young in communal “villages,” Aza reveals the startling complexity of animal communication and what it teaches us about our own. During the course of their conversation, Reid, Aria and Aza explore why recognizing the intelligence of the animal kingdom might spark a new Copernican Revolution, one that changes not just science, but who we believe ourselves as a species to be. It’s a thought provoking journey through language, empathy, and the limits of human perspective that will make you listen to the natural world a little differently. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 00:00 – Live introduction from the Masters of Scale Summit 00:58 – Aza Raskin explains the Earth Species Project and its mission 03:03 – How AI can decode animal language and culture 05:18 – Crows, whales, and dolphins—evidence of communication and community 07:32 – What we’ve missed by only “hearing the shouts” of other species 08:30 – Dolphins learning to innovate together and what it reveals about intelligence 09:57 – Elephants’ overlapping calls and the idea of “communal grammar” 12:33 – From speaking to listening: the ethics of interspecies understanding 14:23 – Names, self-awareness, and identity across dolphins, elephants, and belugas 16:05 – Animal rituals, drum languages, and AI’s early attempts at conversation 18:10 – Animal Language Processing as science’s next frontier 20:38 – The moral shift: what animals teach us about empathy, AI, and responsibility Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.

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• Reid riffs on fostering trust with founders, in boardrooms, and in AI

  In this week's episode, Reid and Aria unpack why trust is a practical skill, not just a feeling. Reid riffs on the importance of hands-on investor-founder relationships, boardroom decisions that can make or break a company, and investor behaviors that build durable trust. They also discuss what product teams and policymakers must do to earn user confidence in an age of AI. Along the way, Reid shares personal anecdotes regarding his work with OpenAI, crisis leadership, and bridging Silicon Valley policy with the rest of the globe. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/

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• David Fajgenbaum on drug repurposing, AI, and saving his own life

  How can AI really help advance medicine? Should patients and care teams be seeking second opinions from LLMs? This week, Reid and Aria sit down with physician-scientist Dr. David Fajgenbaum, who repurposes existing drugs to save lives—including his own. David shares his journey from receiving last rites as a young medical student to co-founding Every Cure, a nonprofit using AI to come up with ways existing drugs can be repurposed to treat every disease and every patient possible. On this special episode, filmed live in New York City, David, Reid, and Aria explore the circuit of hope, action, and impact that drives medical discovery; the technical and ethical challenges around accelerating AI in healthcare; “agent optimization” as the new “search engine optimization;” and what a future of faster diagnoses and treatment could look like. The result is a conversation about resilience, innovation, and unlocking cures that are already within our reach. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/  Topics: 3:00 - Hellos and intros 3:29 - A promise to his mother and the origin of AMF 6:23 - From grief support to medical school 9:18 - Near-death experiences and founding a research network 14:38 - What kept David going at death’s door 16:19 - Discovering a potential treatment and testing it on himself 19:42 - Why drug repurposing is a faster, cheaper complement to drug discovery 22:14 - Co-founding Every Cure and scaling discovery with AI 25:20 - Demo: Building MATRIX and how the algorithm makes predictions 28:41 - Breast cancer and Lidocaine as a case study 30:07 - Why human review is essential in AI for medicine 34:08 - Car exhaust fumes example and FDA pathways 37:31 - Reid’s surprise million-dollar donation for Every Cure compute 39:24 - What AI can unlock across healthcare 41:46 - Building an impact team to close the repurposing loop 47:32 - Improving systemic incentives for generics 54:58 - FDA approval pathways and label change challenges 57:21 - Three life-saving repurposing stories 1:02:20 - Rapid-fire questions Select mentions:  Hidden Potential by Adam Grant Chasing My Cure by Dr. David Fajgenbaum Every Cure  David’s TED Talk: https://youtu.be/sb34MfJjurc?si=GcVleWHZuJ9MqLgS Manas AI Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.

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• Reid riffs on Trump’s $100K visa fee, 3-day work weeks, and AI trust issues

  This week, Reid and Aria dive into the debate over new $100,000 fees on H-1B visas, and discuss how immigration powers U.S. innovation and how to ensure startups aren’t shut out. They also cover developers’ mixed feelings about using AI in coding, the leap from 60% to 85% accuracy in medical AI predictions, and what it will take to bring regulators and clinicians on board. Plus, Reid shares why he’s skeptical of a three-day work week and reflects on the Trust in American Institutions Challenge, highlighting some inspiring finalists. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/

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