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Shirtloads of Science

Dr Karl Kruszelnicki
Shirtloads of Science
Latest episode

450 episodes

  • Shirtloads of Science

    The Rise In Nitrous Misuse with Assoc. Prof. Angela Chiew (463)

    28/02/2026 | 27 mins.
    Nitrous oxide (better known as "laughing gas") is widely used in medicine as a safe anaesthetic and pain reliever. It's also found in whipped cream canisters and even used in car engines. But Angela Chiew, toxicologist and Associate Professor at UNSW, joins me to set the record straight: the growing recreational misuse of this easily accessible gas is causing serious long-term harm, including nerve damage, cognitive damage, weakening of the spinal cord and mobility impairments. 

    Cases of misuse are rising globally, likely driven by how easy it is to legally purchase the drug in many countries. This episode unpacks the hidden dangers behind a gas many once thought was just a harmless high.

    Linkedin: Angela Chiew
    X: AngelaChiewA
  • Shirtloads of Science

    Will AI Take Our Jobs? Part Three of the Great AI Safety Debrief with Dr. Petr Lebedev (462)

    21/02/2026 | 28 mins.
    In the final episode of the Great AI Safety Debrief series with Dr. Petr Lebedev, we discuss job eradication, AI alignment and the rise in cases of AI deceiving humans. Petr unpacks ideas like AI scheming, situation awareness, parasitic relationships between humans and machines, and even the possibility of AI developing belief systems of its own. We end by zooming out to existential risk, Alan Turing's early warnings, and why aligning AI with human values may be one of the most difficult (and urgent) challenges humanity must face.

    Linkedin: Petr Lebedev
    palisaderesearch.org/
  • Shirtloads of Science

    Is AI Outsmarting Us? Part Two of the Great AI Safety Debrief with Dr. Petr Lebedev (461)

    14/02/2026 | 23 mins.
    In part two, Dr. Petr Lebedev and I dive deeper into how modern AI systems are grown, not programmed, and the emergence of Shutdown Resistance. We explore AI performance in math and coding competitions, the rapid evolution of ChatGPT models, and why companies are already letting AI write the majority of their code. Petr explains how huge investments globally are pushing these systems forward faster than we can fully understand or control.

    The final episode in this 3 part series drops next week!

    Linkedin: Petr Lebedev
    palisaderesearch.org/
  • Shirtloads of Science

    The Great AI Safety Debrief Part One with Dr. Petr Lebedev (460)

    07/02/2026 | 24 mins.
    Intelligence is emerging from sand and less than 1% of the population seems to care!

    Physicist and science communicator Dr. Petr Lebedev joins the podcast following his SXSW talk to explore the rapid advancement of AI and how it's dramatically shifting the global status quo. From completing a PhD in physics and writing for Veritasium, to leading science communication at Palisade Research, Petr steps in to bring some clarity to the weird, wild, and worrying sides of AI.

    Did you know that no one truly understands how large language models actually work? We go deep on misaligned systems, humanoid and dog robots, and why many experts believe AI could pose a serious global risk. Is AI our greatest tool? Or something we're slowly losing control of? This conversation is big, so we've split it into three parts. Part two drops next week.
  • Shirtloads of Science

    The Milky Way's Mysterious Glow with Prof. Geraint Lewis (459)

    31/01/2026 | 32 mins.
    A mysterious glow from the centre of the Milky Way has scientists intrigued. Astrophysicist Geraint Lewis explains how this gamma-ray excess, first detected in 2009, could be evidence of dark matter particles interacting deep in our galaxy. With dark matter believed to make up a vast, invisible halo that holds galaxies together, uncovering the source of this glow may bring us closer to understanding what the universe is really made of.
    www.geraintflewis.com/
    Linkedin: geraint-lewis-4a499b1

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About Shirtloads of Science

Dr Karl's a curious optimist – a great combination for a science lover. Join him and his guests for weird facts, amazing conversation and remember, it's never too late for a happy childhood. https://drkarl.com/
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