Plain English with Derek Thompson

Why do placebo effects work, even when patients know that they're taking a sugar pill? How do "nocebo" effects work, and why do some people hold onto beliefs that they suspect might bring them pain and suffering? What do the major world religions have to teach secular athletes and workers about the power of belief, and what does the psychological research tell us about the benefits of prayer, even for those who don't believe in God? Nir Eyal, bestselling author of the new book Beyond Belief, joins the show to talk about the research behind how our beliefs shape our lives.

Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson

If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek Thompson

Guest: Nir Eyal

Producer: Devon Baroldi

Today’s open is adapted from Derek’s Substack essay “If Placebos Work So Well, Why Not Prescribe Sugar Pills For Everything?”
Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Strait of Hormuz is the tiny bottleneck that could destabilize the global economy. As a critical passageway for crude oil, natural gas, and critical inputs for fertilizer, computer chips, and plastic, this small stretch of water is a tiny chokepoint for global trade, and the war in Iran has all but shut it down. What does this mean for the U.S. economy and other countries around the world?  Geopolitical analyst Rachel Ziemba joins the show to discuss.

Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson

If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek Thompson

Guest: Rachel Ziemba

Producer: Devon Baroldi
Learn more about your ad choices. Visit podcastchoices.com/adchoices

What happens when the two biggest stories in the world—the Trump White House and the development of advanced artificial intelligence—collide? Well, nothing good, apparently. When contract negotiations broke down between the Pentagon and Anthropic, a leading AI lab, the Department of War took the extraordinary step of labeling Anthropic a "supply chain risk," a designation typically reserved for Chinese companies suspected of spying on American technology.

It’s not just liberals like me that found this announcement jarring. The technology writer Dean Ball—who served as Senior Policy Advisor for AI at the White House as recently as last summer—said the decision amounted to a nearly tyrannical attack on private property. (After all, if the government can walk up to your company, make you a deal, and destroy your company if you say no, that certainly sounds like a world in which the state can destroy whatever it trains its eyes on.)

So, I wanted to talk to Dean about what he sees—and why he thinks this episode is so important, and so terrifying. Today, we talk about the difference between Biden and Trump’s approach to artificial intelligence before diving into the Anthropic mess, and pulling out of it the bigger story, according to Dean: that Trump’s scattershot AI policy is just the latest sign that AI’s capabilities are growing faster than many people want to admit—this technology is going somewhere fast, and the the American government simply is not prepared for where it’s taking us.

Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson

If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek Thompson

Guest: Dean Ball

Producer: Devon Baroldi
Learn more about your ad choices. Visit podcastchoices.com/adchoices

Donald Trump’s polling has continued to edge down week after week. And yet approval of the Democratic Party is still stuck near its all-time low, according to Gallup and other surveys.

One interpretation of these polls is that the deep unpopularity of the party is an albatross around the neck of Democratic candidates. But there’s another interpretation that I think is more interesting—and perhaps more true. The fact that the party has no clearly defined national leader, and no clearly defined “brand” (sorry), is an opportunity for young Democrats to define themselves as individuals. Rather than act like a congregation all singing from the same hymnal, they can experiment, disagree, and adapt their message to their electorate. And that might ultimately prove to be a strength of the party heading into the 2026 midterms rather than a weakness.

Senator Ruben Gallego (D-Arizona) joins the show to talk about the Iran war, immigration, affordability vs. aspiration, and the future of the Democratic Party.

Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson

If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek ThompsonGuest: Ruben GallegoProducer: Devon Baroldi
Learn more about your ad choices. Visit podcastchoices.com/adchoices

Dramatic regime change. Moderate regime evolution. A calamitous regional conflict. Or … no change at all. Today we consider how the Iran conflict might evolve following the killing of Supreme Leader Khamenei with Karim Sadjadpour, an American policy analyst at the Carnegie Endowment for International Peace.

Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson

If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek ThompsonGuest: Karim SadjadpourProducer: Devon Baroldi
Learn more about your ad choices. Visit podcastchoices.com/adchoices