Science Friday

• How Trump’s DEI Ban Will Affect Medical Research

  Changes limiting programs, grants, and even the nature of studies are already underway at the NIH, NSF, FDA, CDC, and more.On President Trump’s first day in office, he signed an executive order to end what he calls “illegal and immoral discrimination programs,” referencing diversity, equity, and inclusion (DEI) in the federal government. The repercussions of this are already being felt across science agencies.Things are changing fast: Last week, a federal judge in Maryland temporarily blocked parts of the DEI purge from being carried out. At the same time, federal research agencies have already made changes. For example, the National Institutes of Health suddenly pulled a program that provides grants to PhD students from marginalized backgrounds, and has already canceled studies mid-project, like one on LGBTQ cancer patients. The National Science Foundation has begun reviewing active research science projects that may not comply with Trump’s executive orders. The Centers for Disease Control and Prevention took down resources for HIV prevention, LGBTQ+ health, contraception, and more—then partially restored them, as ordered by a judge. And the Food and Drug Administration pulled its guidance on the importance of having some diversity in clinical trials, like those to test drugs and medical devices.So, what does banning diversity, equity, and inclusion efforts mean for medical research? And what does it mean for our health?Host Flora Lichtman talks with Dr. Rachel Hardeman, director of the Center for Antiracism Research for Health Equity at the University of Minnesota in Minneapolis; and Dr. Melissa Simon, an ob-gyn at Northwestern Medicine, and director of the Center for Health Equity Transformation in Chicago.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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• Conflicting Directives Sow Confusion For NIH Workers | The Mycobiome

  The acting head of the NIH reportedly pushed back against legal guidance to resume grant funding, leaving federal workers in the lurch. Also, though fungi make up a tiny part of the human microbiome, they play an important role in both the prevention and development of many diseases.Cuts And Conflicting Directives Sow Confusion For NIH WorkersJust over a month after President Trump’s inauguration, federal science in the US is in a state of disarray. Executive orders to halt grant funding at the National Institutes of Health (NIH) have faced court challenges. Last week, a federal judge extended a restraining order on a proposal to cap NIH grant funding for indirect costs, costs that experts say are critical to their work. But according to new reporting, staff within the NIH have been left without clear guidance about moving forward with those grants, with the NIH’s acting director reportedly pushing back against legal guidance from the agency’s lawyers to restart distribution of the funding.Host Flora Lichtman is joined by Katherine J. Wu, staff writer for The Atlantic, who reported on the turmoil at the NIH. They also talk about other science news of the week, including an update on the measles outbreak in Texas, how to see every planet in the solar system this week, and how scientists think runner Faith Kipeygon could be the first woman to break a four-minute mile.You’ve Heard Of The Microbiome—Welcome To The MycobiomeYou’ve heard of the microbiome, the community of bacteria, viruses, archaea parasites, and fungi that live in our bodies. But that last member of the group, fungi, get a lot less attention than the others. And perhaps that’s unsurprising. After all, bacteria outnumber fungi 999 to 1 in our guts.But now, scientists are beginning to piece together just how important fungi truly are. Disruption in the fungal balance can play a role in the development of Crohn’s disease, irritable bowel disease, celiac disease, colorectal cancer, some skin diseases, and more.Host Flora Lichtman talks with Dr. Mahmoud Ghannoum, microbiologist and professor at Case Western Reserve University’s School of Medicine, who has dedicated his career to studying the fungi in our bodies, and coined the term mycobiome over a decade ago.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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• The Best Tail For Balance | Bindi Irwin Wants Kids To Become ‘Wildlife Warriors’

  The bone and joint structures in mammal tails help them keep their balance. Could those benefits be adapted for robots? And, in her first children’s book, conservationist Bindi Irwin takes little readers on a journey through Australia Zoo.In Search Of The Best Tail For BalanceIf you have met a cat, you’ve probably at some point been amazed by how acrobatic they are. They’re able to reorient themselves effortlessly, even in midair. It turns out that a lot of that twistiness comes down to having a top-tier tail. While most reptile tails can swing only in one plane of movement, mammal tails have more joints, leading to better inertial control. That lets mammals tweak their balance better, much as holding a balance pole can help an acrobat navigate a tightrope.In a recent study published in the Journal of the Royal Society Interface, researchers explored the biomechanics of different tails, and considered how a better tail could help build a better robot. Dr. Talia Moore, a roboticist at the University of Michigan, and Dr. Ceri Weber, a cellular and developmental biology postdoc at UC San Diego, join Host Flora Lichtman to talk tails.Bindi Irwin Encourages Kids To Become ‘Wildlife Warriors’Almost 30 years ago, conservationists Terri Irwin and the late Steve Irwin captured the world’s attention with their show “The Crocodile Hunter.” It introduced millions of people to Australia Zoo and the strange, often scary, sometimes cute, critters from Down Under.Now, Terri and her children—Bindi and Robert—are at the helm of the zoo, which is the setting for Bindi’s new children’s book, You Are a Wildlife Warrior!: Saving Animals & the Planet. In it, Bindi takes little readers and her own daughter, Grace, on an adventure through the zoo.Host Flora Lichtman talks with Bindi about her family’s legacy, how motherhood fuels her approach to conservation, and what it’s like to run a zoo.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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• A Vaccine For Pancreatic Cancer Continues To Show Promise

  Pancreatic cancer is notoriously difficult to treat, and about 90% of diagnosed patients die from the disease. A team at Memorial Sloan Kettering has been working to improve those outcomes by developing a new mRNA vaccine for pancreatic cancer.A few years ago, the team embarked on a small trial to test the vaccine’s safety. Sixteen patients with pancreatic cancer received it, and even though it was a small study, the results were promising: Half the participants had an immune response, and in those patients the cancer hadn’t relapsed after 18 months.This week, the team released a new study in Nature following those same patients, and found six out of eight who responded to the vaccine in the first study did not have their cancer return more than three years later.Joining host Flora Lichtman to talk about these results, and what they could mean for the future of cancer treatment, is study author and surgeon Dr. Vinod Balachandran, director of The Olayan Center for Cancer Vaccines at Memorial Sloan Kettering, based in New York City.Transcripts for each segment will be available after the show airs on sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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• Why Are Flu And Other Viral Infection Rates So High This Year?

  It’s been an unusually tough winter virus season. Rates of flu-like infections are higher than they’ve been in nearly 30 years. And for the first winter since the start of the COVID-19 pandemic, flu deaths have surpassed COVID deaths. Add to that a higher-than-average year for norovirus, a nasty type of stomach bug.Then there’s the emerging threat of avian flu. While there is no evidence of human-to-human transmission of the virus, about 70 people in the US have contracted the virus from livestock since April 2024.To make sense of the latest viral trends, Host Flora Lichtman talks with Dr. Katelyn Jetelina, epidemiologist and author of the newsletter “Your Local Epidemiologist”; and Dr. Erica Shenoy, chief of infection control at Mass General Brigham hospital.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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