Talk Python To Me

Your cloud SSD is sitting there, bored, and it would like a job. Today we’re putting it to work with DiskCache, a simple, practical cache built on SQLite that can speed things up without spinning up Redis or extra services. Once you start to see what it can do, a universe of possibilities opens up. We're joined by Vincent Warmerdam to dive into DiskCache.

Episode sponsors

Talk Python Courses

Python in Production

Links from the show

diskcache docs: grantjenks.com

LLM Building Blocks for Python course: training.talkpython.fm

JSONDisk: grantjenks.com

Git Code Archaeology Charts: koaning.github.io

Talk Python Cache Admin UI: blobs.talkpython.fm

Litestream SQLite streaming: litestream.io

Plash hosting: pla.sh

Watch this episode on YouTube: youtube.com

Episode #534 deep-dive: talkpython.fm/534

Episode transcripts: talkpython.fm

Theme Song: Developer Rap

🥁 Served in a Flask 🎸: talkpython.fm/flasksong

---== Don't be a stranger ==---

YouTube: youtube.com/@talkpython

Bluesky: @talkpython.fm

Mastodon: @[email protected]

X.com: @talkpython

Michael on Bluesky: @mkennedy.codes

Michael on Mastodon: @[email protected]

Michael on X.com: @mkennedy

Today on Talk Python, the creators behind FastAPI, Flask, Django, Quart, and Litestar get practical about running apps based on their framework in production. Deployment patterns, async gotchas, servers, scaling, and the stuff you only learn at 2 a.m. when the pager goes off. For Django, we have Carlton Gibson and Jeff Triplet. For Flask, we have David Lord and Phil Jones, and on team Litestar we have Janek Nouvertné and Cody Fincher, and finally Sebastián Ramírez from FastAPI is here. Let’s jump in.

Episode sponsors

Talk Python Courses

Python in Production

Links from the show

Carlton Gibson - Django: github.com

Sebastian Ramirez - FastAPI: github.com

David Lord - Flask: davidism.com

Phil Jones - Flask and Quartz(async): pgjones.dev

Yanik Nouvertne - LiteStar: github.com

Cody Fincher - LiteStar: github.com

Jeff Triplett - Django: jefftriplett.com

Django: www.djangoproject.com

Flask: flask.palletsprojects.com

Quart: quart.palletsprojects.com

Litestar: litestar.dev

FastAPI: fastapi.tiangolo.com

Coolify: coolify.io

ASGI: asgi.readthedocs.io

WSGI (PEP 3333): peps.python.org

Granian: github.com

Hypercorn: github.com

uvicorn: uvicorn.dev

Gunicorn: gunicorn.org

Hypercorn: hypercorn.readthedocs.io

Daphne: github.com

Nginx: nginx.org

Docker: www.docker.com

Kubernetes: kubernetes.io

PostgreSQL: www.postgresql.org

SQLite: www.sqlite.org

Celery: docs.celeryq.dev

SQLAlchemy: www.sqlalchemy.org

Django REST framework: www.django-rest-framework.org

Jinja: jinja.palletsprojects.com

Click: click.palletsprojects.com

HTMX: htmx.org

Server-Sent Events (SSE): developer.mozilla.org

WebSockets (RFC 6455): www.rfc-editor.org

HTTP/2 (RFC 9113): www.rfc-editor.org

HTTP/3 (RFC 9114): www.rfc-editor.org

uv: docs.astral.sh

Amazon Web Services (AWS): aws.amazon.com

Microsoft Azure: azure.microsoft.com

Google Cloud Run: cloud.google.com

Amazon ECS: aws.amazon.com

AlloyDB for PostgreSQL: cloud.google.com

Fly.io: fly.io

Render: render.com

Cloudflare: www.cloudflare.com

Fastly: www.fastly.com

Watch this episode on YouTube: youtube.com

Episode #533 deep-dive: talkpython.fm/533

Episode transcripts: talkpython.fm

Theme Song: Developer Rap

🥁 Served in a Flask 🎸: talkpython.fm/flasksong

---== Don't be a stranger ==---

YouTube: youtube.com/@talkpython

Bluesky: @talkpython.fm

Mastodon: @[email protected]

X.com: @talkpython

Michael on Bluesky: @mkennedy.codes

Michael on Mastodon: @[email protected]

Michael on X.com: @mkennedy

Python in 2025 is in a delightfully refreshing place: the GIL's days are numbered, packaging is getting sharper tools, and the type checkers are multiplying like gremlins snacking after midnight. On this episode, we have an amazing panel to give us a range of perspectives on what matter in 2025 in Python. We have Barry Warsaw, Brett Cannon, Gregory Kapfhammer, Jodie Burchell, Reuven Lerner, and Thomas Wouters on to give us their thoughts.

Episode sponsors

Seer: AI Debugging, Code TALKPYTHON

Talk Python Courses

Links from the show

Python Software Foundation (PSF): www.python.org

PEP 810: Explicit lazy imports: peps.python.org

PEP 779: Free-threaded Python is officially supported: peps.python.org

PEP 723: Inline script metadata: peps.python.org

PyCharm: www.jetbrains.com

JetBrains: www.jetbrains.com

Visual Studio Code: code.visualstudio.com

pandas: pandas.pydata.org

PydanticAI: ai.pydantic.dev

OpenAI API docs: platform.openai.com

uv: docs.astral.sh

Hatch: github.com

PDM: pdm-project.org

Poetry: python-poetry.org

Project Jupyter: jupyter.org

JupyterLite: jupyterlite.readthedocs.io

PEP 690: Lazy Imports: peps.python.org

PyTorch: pytorch.org

Python concurrent.futures: docs.python.org

Python Package Index (PyPI): pypi.org

EuroPython: tickets.europython.eu

TensorFlow: www.tensorflow.org

Keras: keras.io

PyCon US: us.pycon.org

NumFOCUS: numfocus.org

Python discussion forum (discuss.python.org): discuss.python.org

Language Server Protocol: microsoft.github.io

mypy: mypy-lang.org

Pyright: github.com

Pylance: marketplace.visualstudio.com

Pyrefly: github.com

ty: github.com

Zuban: docs.zubanls.com

Jedi: jedi.readthedocs.io

GitHub: github.com

PyOhio: www.pyohio.org

Watch this episode on YouTube: youtube.com

Episode #532 deep-dive: talkpython.fm/532

Episode transcripts: talkpython.fm

Theme Song: Developer Rap

🥁 Served in a Flask 🎸: talkpython.fm/flasksong

---== Don't be a stranger ==---

YouTube: youtube.com/@talkpython

Bluesky: @talkpython.fm

Mastodon: @[email protected]

X.com: @talkpython

Michael on Bluesky: @mkennedy.codes

Michael on Mastodon: @[email protected]

Michael on X.com: @mkennedy

Have you ever thought about getting your small product into production, but are worried about the cost of the big cloud providers? Or maybe you think your current cloud service is over-architected and costing you too much? Well, in this episode, we interview Michael Kennedy, author of "Talk Python in Production," a new book that guides you through deploying web apps at scale with right-sized engineering.

Episode sponsors

Seer: AI Debugging, Code TALKPYTHON

Agntcy

Talk Python Courses

Links from the show

Christopher Trudeau - guest host: www.linkedin.com

Michael's personal site: mkennedy.codes

Talk Python in Production Book: talkpython.fm

glances: github.com

btop: github.com

Uptimekuma: uptimekuma.org

Coolify: coolify.io

Talk Python Blog: talkpython.fm

Hetzner (€20 credit with link): hetzner.cloud

OpalStack: www.opalstack.com

Bunny.net CDN: bunny.net

Galleries from the book: github.com

Pandoc: pandoc.org

Docker: www.docker.com

Watch this episode on YouTube: youtube.com

Episode #531 deep-dive: talkpython.fm/531

Episode transcripts: talkpython.fm

Theme Song: Developer Rap

🥁 Served in a Flask 🎸: talkpython.fm/flasksong

---== Don't be a stranger ==---

YouTube: youtube.com/@talkpython

Bluesky: @talkpython.fm

Mastodon: @[email protected]

X.com: @talkpython

Michael on Bluesky: @mkennedy.codes

Michael on Mastodon: @[email protected]

Michael on X.com: @mkennedy

For years, building interactive widgets in Python notebooks meant wrestling with toolchains, platform quirks, and a mountain of JavaScript machinery. Most developers took one look and backed away slowly. Trevor Manz decided that barrier did not need to exist. His idea was simple: give Python users just enough JavaScript to unlock the web’s interactivity, without dragging along the rest of the web ecosystem. That idea became anywidget, and it is quickly becoming the quiet connective tissue of modern interactive computing. Today we dig into how it works, why it has taken off, and how it might change the way we explore data.

Episode sponsors

Seer: AI Debugging, Code TALKPYTHON

PyCharm, code STRONGER PYTHON

Talk Python Courses

Links from the show

Trevor on GitHub: github.com

anywidget GitHub: github.com

Trevor's SciPy 2024 Talk: www.youtube.com

Marimo GitHub: github.com

Myst (Markdown docs): mystmd.org

Altair: altair-viz.github.io

DuckDB: duckdb.org

Mosaic: uwdata.github.io

ipywidgets: ipywidgets.readthedocs.io

Tension between Web and Data Sci Graphic: blobs.talkpython.fm

Quak: github.com

Walk through building a widget: anywidget.dev

Widget Gallery: anywidget.dev

Video: How do I anywidget?: www.youtube.com

PyCharm + PSF Fundraiser: pycharm-psf-2025 code STRONGER PYTHON

Watch this episode on YouTube: youtube.com

Episode #530 deep-dive: talkpython.fm/530

Episode transcripts: talkpython.fm

Theme Song: Developer Rap

🥁 Served in a Flask 🎸: talkpython.fm/flasksong

---== Don't be a stranger ==---

YouTube: youtube.com/@talkpython

Bluesky: @talkpython.fm

Mastodon: @[email protected]

X.com: @talkpython

Michael on Bluesky: @mkennedy.codes

Michael on Mastodon: @[email protected]

Michael on X.com: @mkennedy