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a16z Podcast

Andreessen Horowitz
a16z Podcast
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  • Katherine Boyle on Shawn Ryan
    Venture capital has powered companies like Facebook and TikTok—but what if that same urgency fueled America’s defense and industrial base? Katherine Boyle, General Partner at Andreessen Horowitz and cofounder of the firm’s American Dynamism practice, argues this is the biggest business opportunity of our time.In this conversation from The Shawn Ryan Show, Boyle discusses the rise of defense tech startups, why optimism drives her work, and how a new generation of engineers and founders is rethinking innovation and patriotism in America. Timecodes: 0:00 Introduction 0:41 Patriotism, Optimism, and American Innovation4:27 Startups vs. Legacy Primes in Defense10:08 Venture Capital’s Unique Incentives17:21 Katherine’s Backstory: Family & Upbringing21:07 The Decline of Community & Family Pillars23:23 Polarization, Religion, and Social Fabric26:16 America’s Birth Rate Crisis29:46 Cultural Shifts and the Family Structure42:01 Katherine’s Path: Journalism to Venture Capital1:06:06 Breaking into Silicon Valley1:18:06 Investing in Defense: The Anduril Story1:37:37 The American Dynamism Movement2:04:27 Manufacturing, Space, and the Future of Defense2:14:06 Espionage, China, and National Security2:37:38 The Attack on the American Family2:48:29 Cultural Change, Suffering, and Purpose2:55:30 Closing Thoughts Resources: Find Katherine on X: https://x.com/KTmBoyleShawn Ryan Show Links YouTube:  https://www.youtube.com/channel/UCkoujZQZatbqy4KGcgjpVxQ/joinListen on Apple: https://podcasts.apple.com/us/podcast/shawn-ryan-show/id1492492083Listen on Spotify: https://open.spotify.com/show/5eodRZd3qR9VT1ip1wI7xQ?si=7abec4d61c324b24 Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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  • Monopolies vs Oligopolies in AI
    In this interview from the 20VC podcast, Martin Casado (a16z General Partner) joins Harry Stebbings to unpack the state of AI, the rise of coding models, the future of open vs. closed source, and how value is shifting across the stack.Martin offers a candid view of the opportunities and dangers shaping AI and venture capital today. Resources: Find Martin on X: https://x.com/martin_casadoFind Harry on X: https://x.com/harrystebbingsMore about 20VC:Subscribe on YouTube: https://www.youtube.com/@20VCSubscribe on Spotify:https://open.spotify.com/show/3j2KMcZTtgTNBKwtZBMHvl?si=85bc9196860e4466&nd=1&dlsi=d1dbbc6a0d7c4408Subscribe on Apple Podcasts:https://podcasts.apple.com/us/podcast/the-twenty-minute-vc-20vc-venture-capital-startup/id958230465Visit their Website: https://www.20vc.comSubscribe to their Newsletter: https://www.thetwentyminutevc.com/Follow 20VC on Instagram:  https://www.instagram.com/20vchq/#Follow 20VC on TikTok: https://www.tiktok.com/@20vc_tok Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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  • The Top 100 Most Used AI Apps in 2025
    What are real consumers actually doing with AI today?In this episode, a16z consumer investors Olivia Moore and Justine Moore break down the fifth edition of our Consumer AI 100, a biannual ranking of the most used AI-native web and mobile products across the globe. Timecodes:  0:00 Introduction1:45 New Companies & Trends3:32 Companionship & Creative Tools4:20 Big Tech on the List: Google’s Impact6:24 Chinese AI Companies & Global Trends10:19 Vibecoding: A New Trend13:40 AI All-Stars: Consistent Top Performers15:30 Network Effects & Product Experience17:20 Enterprise Adoption & Prosumer Growth19:40 Biggest Takeaways21:09 Grok's debut22:56 Future predictions25:14 Closing & Audience Engagement Resources:Read more about the Top Gen 100: http://a16z.com/100-gen-ai-apps-5/Find Olivia on X: https://x.com/omooretweetsFind Justine on X: https://x.com/venturetwins Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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  • Aaron Levie and Steven Sinofsky on the AI-Worker Future
    What exactly is an AI agent, and how will agents change the way we work?In this episode, a16z general partners Erik Torenberg and Martin Casado sit down with Aaron Levie (CEO, Box) and Steven Sinofsky (a16z board partner; former Microsoft exec) to unpack one of the hottest debates in AI right now.They cover:Competing definitions of an “agent,” from background tasks to autonomous internsWhy today’s agents look less like a single AGI and more like networks of specialized sub-agentsThe technical challenges of long-running, self-improving systemsHow agent-driven workflows could reshape coding, productivity, and enterprise softwareWhat history — from the early PC era to the rise of the internet — tells us about platform shifts like this oneThe conversation moves from deep technical questions to big-picture implications for founders, enterprises, and the future of work. Timecodes: 0:00 Introduction: The Evolution of AI Agents0:36 Defining Agency and Autonomy1:54 Long-Running Agents and Feedback Loops4:49 Specialization and Task Division in AI6:20 Human-AI Collaboration and Productivity6:59 Anthropomorphizing AI and Economic Impact9:10 Predictions, Progress, and Platform Shifts11:31 Recursive Self-Improvement and Technical Challenges13:20 Hallucinations, Verification, and Expert Productivity16:20 The Role of Experts and Tool Adoption22:14 Changing Workflows: Agents Reshaping Work Patterns45:55 Division of Labor, Specialization, and New Roles48:47 Verticalization, Applied AI, and the Future of Agents54:44 Platform Competition and the Application Layer55:29 Closing Thoughts and Takeaways  Resources: Find Aaron on X: https://x.com/levieFind Martin on X: https://x.com/martin_casadoFind Steven on X: https://x.com/stevesi Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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  • Ben Horowitz on How a16z Was Built
    Erik Torenberg sits down with Ben Horowitz, Cofounder of a16z, for a candid conversation on venture capital, leadership, and the future of innovation. Recorded live at a16z’s Menlo Park offices in 2023, Ben shares practical wisdom and hard-earned lessons on navigating market cycles, building resilient companies, and why culture is a lasting competitive edge.Timecodes: 0:00 Introduction 0:49 Building a Lasting Venture Firm1:57 Product vs. Investor-Driven Firms5:17 Evolution of Andreessen Horowitz8:43 Fund Sizing & Market Opportunity11:38 Recruiting & Culture at a16z13:58 Supporting Founders & Firm Mission14:39 Governance & Firm Structure17:15 The Future of Venture Capital20:26 Riding Trends: AI, Web3, and Beyond27:06 Regulation, Open Source, and Innovation29:22 LPs, Macro, and Long-Term Strategy33:25 Advice for the Next Generation37:15 Tech Optimism & Societal Impact42:33 Closing Thoughts & Outro Resources: Find Ben on X:  https://x.com/bhorowitzSubscribe to Turpentine VC: link.chtbl.com/TurpentineVC Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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About a16z Podcast

The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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