The Next Big Idea

Nicholas Thompson, CEO of The Atlantic and host of "The Most Interesting Thing in AI," joins Rufus and Caleb to explain why the machines may master our minds long before they master our muscles — and what that gap tells us about where AI is headed. Along the way: why human podcasters still beat AI ones, how Nick learned to stop worrying and love open source, and where he'd point an infinite AI budget.

🎧 Check out Nick’s previous appearance on the show here.

📦 Join the Next Big Idea Club and we’ll send you a copy of David Epstein’s new book, Inside the Box, and an invitation to a members-only Q&A with David on May 26. Learn more at nextbigideaclub.com/

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The Greek philosopher Epicurus made a rather bold claim over two thousand years ago. The key to life, he said, is simple: pursue pleasure and avoid pain. Around this maxim he developed a school of philosophy, Epicureanism, which promised its adherents that if they took care of their basic needs, surrounded themselves with trustworthy friends, and developed a basic understanding of science, they would be happy. But is it really that simple? Can the advice of someone born 2,363 years ago still hold true? To answer these questions, we turned to Emily Austin, professor of philosophy at Wake Forest University and author of the delightful book Living for Pleasure: An Epicurean Guide to Life.

(This episode first aired in January 2023.)

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You can run from uncertainty, but you can’t hide. The thing to do, says Simone Stolzoff, to develop comfort with ambiguity and build tolerance for the unknown. His new book is How to Not Know: The Value of Uncertainty in a World that Demands Answers.

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In the last 20 years, there has been a dramatic change in our understanding of neuroplasticity — the brain’s capacity to grow new neurons. In the last five years, we’ve learned that your hippocampus, the part of your brain responsible for learning and memory, can get bigger at any age. Majid Fotuhi, who teaches at Johns Hopkins, has been at the forefront of a new body of research demonstrating that lifestyle changes — tweaks to the way you exercise and eat, adjustments to your sleep and mindset — can improve your brain health no matter how old you are. They can even reverse early-stage Alzheimer’s. His new book is The Invincible Brain, and the message is clear: with the right lifestyle and mindset changes, you can grow a bigger brain.

🔗 LINKS AND MENTIONS:

Check out our playlist of health-related episode on Spotify

The Next Big Idea Club — Save 20% on any membership when you use code PODCAST at nextbigideaclub.com

Granola — If meetings are eating up your day, Granola is a no-brainer. You can try it totally free for three months. Just head to granola.ai/idea

Incogni — Protect your personal information online and get an exclusive 60% off an annual plan at incogni.com/nbi

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Is freedom overrated? In his new book, Inside the Box, David Epstein argues that constraints, limits and obstacles are what stimulate creativity, innovation, collaboration and personal contentment.

📦 Get David’s new book delivered straight to your door by joining the Next Big Idea Club! Learn more at nextbigideaclub.com (use code PODCAST for 20% off).

🔗 SPONSORED BY:

Granola — If meetings are eating up your day, Granola is a no-brainer. You can try it totally free for three months. Just head to granola.ai/idea 

Incogni — Protect your personal information online and get an exclusive 60% off an annual plan at incogni.com/nbi 

Quince — Refresh your spring wardrobe and get free shipping and 365-day returns at quince.com/nbi   

Shopify — Launch your business for just $1/month. Start selling today at shopify.com/nbi