NICE Talks

In this episode, we explore the research taking place behind the scenes at NICE and how it helps us prepare for the future of healthcare. From new medicines and digital health technologies to artificial intelligence and innovative ways of using health data, the Research team works with partners across the UK and around the world to tackle some of the biggest challenges facing health and care today.
Associate Director of Research Sarah Fothergill and senior scientific adviser Jamie Elvidge explain how NICE identifies emerging trends, develops new methods for evaluating health technologies, and ensures that future guidance is based on the best available evidence.

You'll find more about the work of the research team, including how to get involved, on our website: https://www.nice.org.uk/what-nice-does/our-research-work/how-to-partner-with-us-in-our-research-work

In this episode, we explore how new machine perfusion technology is changing the landscape of organ transplantation in the UK. NICE has published guidance recommending routine NHS access to specialist devices that keep donated livers and lungs functioning outside the body, potentially unlocking hundreds of organs for transplant each year.

We hear from cardiothoracic surgeon Marius Berman, Clinical Director of the Transplant Programme at Royal Papworth Hospital. And by Monica Walsh, who received a liver transplant almost 10 years ago and now mentors others waiting for transplants.

- Read NICE's guidance on liver preservation machines
- Read NICE's guidance on lung preservation technology

In this episode we explore the draft NICE guideline for PMOS (formerly known as PCOS), out for public consultation until 11 August 2026. We're joined by guideline committee members Aled Rees, professor of endocrinology at Cardiff University, and Sharon Manship, a lay member with lived experience of PMOS. Together they discuss how the recent name change, a new annual review, and a stronger focus on earlier diagnosis could transform care for the estimated 1 in 8 women living with the condition.

Learn more: https://www.nice.org.uk/news/articles/nice-recommends-annual-review-for-pmos-in-new-draft-guideline-aimed-at-improving-diagnosis-and-care
Read the draft guideline: https://www.nice.org.uk/guidance/indevelopment/gid-ng10436/consultation/html-content-9

NICE has recommended teplizumab for NHS use — the first treatment to delay the onset of symptomatic type 1 diabetes by an average of nearly three years.

In this episode, we speak to Lucy Chambers, Head of Research Impact and Communications at Diabetes UK, and Amy Norman, whose daughter Imogen accessed teplizumab through a managed access programme after being identified through the ELSA screening study.

Find out more: NICE recommendation for teplizumab: https://www.nice.org.uk/guidance/gid-ta10981/documents/html-content-10 | ELSA screening study (children aged 2–17): https://www.elsadiabetes.nhs.uk/taking-part/ | T1DRA trial (adults): https://t1dra.bristol.ac.uk/

In this episode we discuss the recent changes to the NICE guideline for neonatal infections, that mean newborn babies receiving antibiotics in hospital could potentially switch to oral antibiotics and be cared for at home, if they are doing well and responding to treatment.

Guests:
• Dr Tim Watts, guideline committee member and Consultant Neonatologist at the Evelina
• Dr Harriet Aughey, Neonatal paediatrician at the Royal Devon and Exeter Hospital and co-lead on the NOAH (Neonatal Oral Antibiotics at Home) project
• Emily Rose Jeffrey, mother to Luna took part in the NOAH trial

Link to neonatal infections guideline: https://www.nice.org.uk/guidance/ng195
Link to news story: https://www.nice.org.uk/news/articles/nice-updates-neonatal-infection-guidance-to-allow-home-antibiotic-treatment-for-some-babies