The Next Wave - AI and The Future of Technology

• Inside Google's AI Lab: Drug Discovery, World AI Model & AlphaEvolve

  Want the ultimate guide to Google's Gemini? Get it here: https://clickhubspot.com/evt Episode 68: How is Google DeepMind pushing the boundaries of AI to tackle drug discovery, robotics, and even autonomous AI agents? Matt Wolfe (https://x.com/mreflow) sits down with DeepMind CEO Sir Demis Hassabis (https://x.com/demishassabis), a neuroscientist, AI pioneer, Nobel laureate, and knight, to peel back the curtain on Google’s latest advances—and the ethical challenges that come with them. In this episode, Matt and Demis go deep on what’s powering the newest generation of AI agents, how models like AlphaFold and AlphaEvolve are accelerating scientific breakthroughs, and why world models are so important for the future of robotics. Demis shares why he believes AI is poised to reshape society—for better and for worse—and what Google is doing to build public trust in its systems. Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd — Show Notes: (00:00) AI Revolutionizing Drug Discovery (03:35) Advanced Model Training Methods (07:06) Accelerating Drug Discovery with AI (11:12) AI's Responsible Role in Society (13:56) AI Revolutionizing Science & Life — Mentions: Sir Demis Hassabis: https://www.linkedin.com/in/demishassabis/ Google DeepMind: https://deepmind.google/ AlphaFold: https://alphafold.ebi.ac.uk/ AlphaEvolve: https://deepmind.google/discover/blog/alphaevolve-a-gemini-powered-coding-agent-for-designing-advanced-algorithms/ Isomorphic Labs: https://www.isomorphiclabs.com/ Android XR glasses: http://blog.google/products/android/android-xr-gemini-glasses-headsets/ Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw — Check Out Matt’s Stuff: • Future Tools - https://futuretools.beehiiv.com/ • Blog - https://www.mattwolfe.com/ • YouTube- https://www.youtube.com/@mreflow — Check Out Nathan's Stuff: Newsletter: https://news.lore.com/ Blog - https://lore.com/ The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano

  --------  

  18:29

  --------

  18:29
• How Tom Bilyeu Uses AI + Why He'll Never Hire Again

  Want Matt's AI Tools Playbook? Get it here: https://clickhubspot.com/dsb Episode 67: What does the future of hiring and creative work look like in an age where A.I. can replace entire departments? Matt Wolfe (https://x.com/mreflow) and Nathan Lands (https://x.com/NathanLands) sit down with Tom Bilyeu (https://x.com/TomBilyeu), co-founder of Quest Nutrition, host of Impact Theory, and founder of Impact Theory Studios, to dig deep into how he’s revolutionized his business with A.I.—and why he may never need to hire the same way again. This episode explores how Tom Bilyeu structures and deploys a five-member A.I. “department” to automate everything from marketing to content creation, and how this approach is reducing headcount without sacrificing creativity. Tom discusses the granular details of training custom GPTs to capture his voice, fact-checking with Grok, A.I.’s impact on indie game development, and what society might look like as technology accelerates. Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd — Show Notes: (00:00) Customizing AI for Specific Tasks (04:48) AI Revolutionizing Content Creation (08:08) Tech Glitch Trauma (11:25) Grok's Detailed Writing Advantage (15:04) AI in Game Development Reception (16:40) Tech Embrace vs. Religious Rejection (21:33) Future of AI in Gaming (22:32) AI Storytelling in Virtual Worlds (25:52) AI: The New Global Hegemon (31:35) Mouse Utopia Experiment Collapse (32:13) Hardship is Essential for Growth (37:51) Virtual Worlds vs Space Exploration (38:54) Tech Integration: Matrix and Beyond (42:10) Year-Round AI Integration (46:41) From Prototype to Product — Mentions: Tom Bilyeu: https://www.youtube.com/c/TomBilyeu Impact Theory: https://podcasts.apple.com/us/podcast/tom-bilyeus-impact-theory/id1191775648 Grok: https://x.ai/ Lovable: https://lovable.dev/ Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw — Check Out Matt’s Stuff: • Future Tools - https://futuretools.beehiiv.com/ • Blog - https://www.mattwolfe.com/ • YouTube- https://www.youtube.com/@mreflow — Check Out Nathan's Stuff: Newsletter: https://news.lore.com/ Blog - https://lore.com/ The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano

  --------  

  52:07

  --------

  52:07
• How I'm Building a Zero-Employee Business with AI

  Want to Automate your work with AI? Get the playbook here: https://clickhubspot.com/wgk Episode 66: Can you really build a zero-employee business with AI? Nathan Lands (https://x.com/NathanLands) sits down with John Rush (https://x.com/johnrushx), founder and self-proclaimed builder of “the most automated org on earth,” to unpack what it takes to launch and run a company where 80% of the work (and soon, 100%) is done by AI agents. John shares his journey from managing large VC-backed teams to going fully solo and using AI to automate nearly every task in his startups, from prototyping and front-end design to sales outreach and SEO content creation. The conversation covers unique agent workflows, how to rapidly test business ideas, how specialized vs. generalist AI agents can supercharge productivity, and practical insights for solopreneurs and founders curious about leveraging automation for scale. Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd — Show Notes: (00:00) Transitioning from Teamwork to AI Entrepreneurship (04:01) Rapid AI Prototyping Strategy (08:40) Specialized vs. General AI Agents (10:25) Automating Marketing with Limited Coding (13:38) Embrace AI Agents' Autonomy (19:09) AI Directories Enhance Contextual Accuracy (22:36) LLMs Prefer Directories Over Blog Posts (23:31) LLMs and Directory Discovery (28:36) Reddit Manipulation Exploits Google's Search Algorithm (30:42) Elon Musk Boosts X Account (34:36) AI Progress Hindered by Infrastructure Constraints (39:11) Limit Screen Time for Balance (42:11) Leveraging AI for Business Innovation (43:07) Weekly Idea Generation Strategy — Mentions: John Rush: https://www.linkedin.com/in/johnrushx/ Unicorn Platform: https://unicornplatform.com/ Grok: https://x.ai/ Replit: https://replit.com/ Cursor: https://cursor.com/en Lindy: https://www.lindy.ai/ Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw — Check Out Matt’s Stuff: • Future Tools - https://futuretools.beehiiv.com/ • Blog - https://www.mattwolfe.com/ • YouTube- https://www.youtube.com/@mreflow — Check Out Nathan's Stuff: Newsletter: https://news.lore.com/ Blog - https://lore.com/ The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano

  --------  

  47:00

  --------

  47:00
• What's Actually Coming in AI (From Someone Building It)

  Episode 65: What’s actually coming next in AI, and how will it transform the fundamental infrastructure we rely on every day? Matt Wolfe (https://x.com/mreflow) sits down with DJ Sampath (https://x.com/djsampath), Senior Vice President of AI Products at Cisco, for a deep dive into the AI-powered future of networking, security, and the enterprise. In this episode, DJ Sampath—former CEO and founder of Armorblox, now leading Cisco’s AI product division—shares an exclusive look at Cisco’s new AI Canvas platform: a generative UI that enables seamless collaboration between humans and AI agents for real-time, intelligent problem solving. Matt and DJ pull back the curtain on how Cisco is modernizing the internet’s backbone, why the enterprise is ground zero for AI-enabled transformation, and the critical new challenges of AI security as agents multiply by the billions. If you want to understand what’s really next in enterprise AI—and how it connects to your own experience as a consumer—don’t miss this fascinating, forward-looking conversation. Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd — Show Notes: (00:00) AI Innovations with Cisco's DJ Sampath (06:06) Enterprises Adopting AI Revolution (09:09) Integrated Cisco Product Connectivity (11:08) AI Surprises: Creativity Unleashed (14:57) Embrace AI for Job Security (16:36) AI Revolutionizes Research Efficiency — Mentions: Want 17 pages of Matt's favorite AI Tools? Get it here: https://clickhubspot.com/vwo DJ Sampath: https://www.linkedin.com/in/djsampath/ Cisco: https://www.cisco.com/ Armorblox: https://www.cisco.com/site/us/en/products/security/secure-email/armorblox/index.html AI Canvas: https://newsroom.cisco.com/c/r/newsroom/en/us/a/y2025/m06/announcing-cisco-ai-canvas-revolutionizing-it-with-agenticops.html — Check Out Matt’s Stuff: • Future Tools - https://futuretools.beehiiv.com/ • Blog - https://www.mattwolfe.com/ • YouTube- https://www.youtube.com/@mreflow — Check Out Nathan's Stuff: Newsletter: https://news.lore.com/ Blog - https://lore.com/ The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano

  --------  

  22:16

  --------

  22:16
• 12 INSANE AI Agent Use Cases in Lindy AI (Live Demo)

  Episode 64: What if you could hire an AI intern to handle your meetings, emails, CRM, and even negotiate refunds over the phone? Nathan Lands (https://x.com/NathanLands) is joined by Flo Crivello (https://x.com/Altimor), founder of Lindy AI, a leading AI agent platform in Silicon Valley. In this episode, Flo gives a revealing look into how Lindy’s AI agents are already replacing entire teams in startups by automating sales outreach, executive assistance, scheduling, meeting notes, CRM, recruiting, and even handling live phone calls and negotiations. Watch live demos, discover the smartest use cases, see how AI agents collaborate, and learn how you can start leveraging these capabilities in your own business. Plus, Flo opens up about where work and productivity are headed as AI interns get smarter and more independent. Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd — Show Notes: (00:00) AI As Versatile Digital Interns (06:04) Calendar Management Preferences (07:34) Automated Meeting Summary Prompt (11:36) AI-Driven Decision Workflow (13:15) AI Filters Sponsorship Emails (18:02) AI Memory and Meeting Transcription (20:43) Use Examples for Better Prompts (25:07) AI Conversations: A Unique Era (26:57) Flight Canceled, Unexpected Refund (30:00) Friday Phone Check-Ins with Elon Lindy (34:15) Deepfakes Overblown, Future of Work (37:51) The Unknowable Future Beyond Singularity (38:29) Post-Work Utopia vs. Tech-Dystopia — Mentions: Want the ultimate guide on AI Agents? Get it here: https://clickhubspot.com/efh Flo Crivello: https://www.linkedin.com/in/florentcrivello/ Lindy: https://www.lindy.ai/ Claude: https://claude.ai/ Greg Isenberg’s interview with Flo: https://podcasts.apple.com/mx/podcast/i-built-a-team-of-ai-agents-that-grow-my-business-24-7-full-demo/id1593424985?i=1000703493519 Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw — Check Out Matt’s Stuff: • Future Tools - https://futuretools.beehiiv.com/ • Blog - https://www.mattwolfe.com/ • YouTube- https://www.youtube.com/@mreflow — Check Out Nathan's Stuff: Newsletter: https://news.lore.com/ Blog - https://lore.com/ The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano

  --------  

  43:04

  --------

  43:04

More Business podcasts

Trending Business podcasts

About The Next Wave - AI and The Future of Technology

The Next Wave - AI and The Future of Technology: Podcasts in Family