The Beyond Tomorrow Podcast with Julian Issa

What if the future of healthcare is already here, just unevenly distributed?

Physician-scientist and innovator Daniel Kraft joins Julian to unpack what’s actually happening right now in health, medicine, and longevity and what’s coming faster than most people realize. From AI-powered wearables and digital twins to personalized cancer vaccines and the rise of “health agents,” Daniel explains why he calls himself a now-ist, not a futurist: the tools to radically improve health already exist, but mindset, incentives, and systems are lagging behind.

They explore the shift from reactive sick care to proactive, personalized health, the promises and dangers of biohacking culture, and why evidence-based medicine still matters in a world flooded with hype. The conversation also tackles big questions around health equity, misinformation, vaccines, and how emerging technologies like AI, genomics, and augmented reality could transform care, if we learn how to integrate them responsibly and humanely. 

What You’ll Learn:
Why the future of medicine is about proactive, continuous care, not yearly checkups

How wearables, genomics, and digital twins could enable truly personalized health

The difference between evidence-based innovation and overhyped biohacking

What AI can (and shouldn’t) replace in healthcare and the doctor-patient relationship

How cancer screening, immunotherapy, and personalized vaccines are evolving

Why incentives, not technology, are often the biggest barrier to better healthcare

How to think critically about longevity trends, supplements, and emerging therapies

⏱ Timestamps00:00 Intro
00:26 The Art of the Possible in Health
01:22 Why Daniel Calls Himself a “Now-ist”
03:09 Curiosity, Gadgets, and Connecting the Dots
04:18 What Are Omics and Why They Matter
07:18 Wearables and the Shift to Proactive Health
09:17 Why Doctors Don’t Prescribe Wearables (Yet)
11:35 We Don’t Practice Healthcare, We Practice Sick Care
13:39 The Danger of Over-Quantifying Your Health
16:23 What the Future of Healthcare Actually Looks Like
19:50 Why Human Connection Still Matters in Medicine
22:18 How AI Will Change the Role of Doctors
24:52 Hospital-to-Home and Care Anywhere
29:41 Incentives: Following the Money in Healthcare
31:45 Why Healthcare Is Ripe for Disruption
33:40 The Rise of Health Agents and Personal AI
34:30 What Is a Digital Twin?
36:37 What a Cancer-Free World Could Look Like
38:29 Cancer Vaccines, Genetics, and Early Detection
40:20 Can We Really Cure Cancer?
42:34 COVID Vaccines, Misinformation, and Science
46:16 The Problem With Health Disinformation
47:54 Why Correlation Is Not Causation
50:27 Separating Science From Snake Oil
52:50 How to Evaluate Health Claims Critically
54:36 What Evidence-Based Medicine Really Means
55:59 Simple Habits That Actually Improve Healthspan
57:12 Longevity Hype vs. What’s Proven
58:46 Gene Therapy and CRISPR’s Real Potential
01:03:01 Stem Cell Therapy: What to Know Before You Try It
01:08:59 AI, Protein Folding, and Drug Discovery
01:10:15 AR, VR, and the Metaverse in Healthcare
01:12:52 What Daniel’s Next TED Talk Will Be About
01:14:41 Who Daniel Thinks About When He Does His Work
01:16:38 Longevity Escape Velocity: Will We Reach It?
01:19:03 What AGI Means for the Future of Health
01:20:46 Daniel’s Final Advice for Living Healthier 

Connect with Julian
📸 Instagram: @thebeyondtomorrowpodcast
🌐 Website: www.beyondtomorrowpodcast.com
📩 Email: [email protected]
🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Follow Daniel:
Website: http://DanielKraftMD.com
LinkedIn: https://www.linkedin.com/in/dkraft   
X: https://x.com/daniel_kraft 
Instagram: https://www.instagram.com/danielkraftmd 
NextMed Health: 
https://www.nextmed.health/  
http://Digital.Health  
http://ContinuumHealth.vc

Should the U.S. just take Greenland because it can?

As the Arctic melts and critical minerals become the new oil, Greenland has gone from forgotten ice sheet to geopolitical prize. In this Davos street debate, world leaders, policy insiders, and global citizens clash over an unthinkable question: should Greenland become a U.S. state or would that cross the line into modern-day imperialism? Some argue it’s a strategic necessity in a world racing toward conflict with China and Russia. Others warn it would shatter NATO, alienate Europe, and revive the ugliest chapters of colonial history.

What starts as a conversation about minerals and defense quickly spirals into something darker: who really gets to decide the fate of a nation? Is this about security or power? Cooperation or coercion? And if borders can change when resources are at stake, is any country truly safe?

This street interview took place in Davos, Switzerland, during the World Economic Forum (WEF) annual meeting, where global leaders, policymakers, executives, and media gather to discuss geopolitics, economics, and global risk. Featuring voices including Kerry Kennedy, @billboardchris, an Arctic defense and security expert, and many more.

⏱ Timestamps
00:00 Should Greenland Become a US State?
03:26 Will the U.S. Invade Greenland?
05:03 Europeans Speak About the Possible Invasion
07:47 The Geographical Factor
10:52 The Arctic is Heating Up

Connect with Julian
📸 Instagram: @thebeyondtomorrowpodcast
🌐 Website: www.beyondtomorrowpodcast.com
📩 Email: [email protected]
🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

What happens when artificial intelligence stops being something we use and starts becoming something that shapes who we are?

Julian sits down with Ramesh Raskar for a hopeful, wide-ranging conversation about where AI is actually headed and where it should go. Instead of leaning into the usual doomsday fears, they talk about a different risk, a future where intelligence is centralized, creativity is squeezed out, and people slowly lose their sense of purpose.

They discuss what an “agentic” future could look like, one where everyone has their own AI agent working on their behalf, not owned by a company but shaped by personal values, goals, and lived experience. They talk about how this could transform healthcare, education, and work, not by replacing humans, but by amplifying what makes human contribution meaningful. There’s a strong emphasis on dignity, pride in craft, and why losing those things could be more damaging than job loss itself.

Ramesh Raskar is an MIT professor, researcher, and inventor whose work spans artificial intelligence, imaging, robotics, and decentralized systems. He has led research teams at Google, Facebook, and Apple, and focuses on building human-centered AI technologies designed to support shared prosperity.

What You’ll Learn:
Why centralized AI risks reducing human agency and purpose
How decentralized AI agents could reshape work, education, and healthcare
The difference between efficiency-driven AI and human-centered intelligence
Why loss of meaning may be a bigger threat than job displacement
How shared prosperity depends on ownership, not just access
What an “agentic society” could look like in practice
Why AI literacy is essential for the decade ahead
How adaptability and learning-to-learn shape human flourishing

⏱ Timestamps
00:00 Intro
00:51 How Can AI Benefit Society?
02:40 The Real Risk of AI Isn’t Doomsday
05:45 From Using AI to Owning AI
10:16 Why Centralized AI Fails
12:25 The Rise of Personal AI
15:10 When Work Loses Meaning
17:38 Why Purpose Still Matters
20:13 A World Where Everyone Has an AI Agent
25:42 Inside an Agentic Society
33:11 How Power and Bias Scale
36:41 Why Decentralization Works
39:07 Lessons From the Internet
44:07 What the World Could Look Like in 2030
47:20 How AI Could Change Healthcare
48:45 Collective Intelligence at Scale
53:55 Who Wins When Data Is Decentralized
56:45 How AI Doomsday Actually Happens
01:01:44 Why Phase One Was Necessary
01:04:20 Why AI Literacy Matters
01:07:20 Learning How to Learn
01:08:22 What Kids Should Learn Today
01:10:05 A Simple Rule for the Future

Want to Follow Ramesh's Mission?
Join here: https://nanda.mit.edu,
projectnanda.org,
join39.org
LinkedIn: https://www.linkedin.com/in/raskar MIT Media Lab: https://www.media.mit.edu/people/raskar/overview/

Connect with Julian
📸 Instagram: @thebeyondtomorrowpodcast
🌐 Website: www.beyondtomorrowpodcast.com
📩 Email: [email protected]
🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

What happens when economic decline, cultural identity, and technological acceleration all collide at once?

Julian sits down with Razib Khan to explore the forces reshaping the US, Europe, and the wider West. They unpack why tariffs, zero-sum thinking, and reactionary politics may be symptoms of deeper structural decline, while also examining why optimism, migration patterns, and cultural norms have historically fueled American dynamism. From Brexit and European stagnation to the rise of populism and questions around national identity, the discussion challenges easy narratives from all sides.

The conversation goes further, tackling some of today’s most sensitive and consequential questions: immigration and integration, multiculturalism, religion in pluralistic societies, and whether shared values still exist in the modern West. They also explore the role of personality, genetics, and culture in shaping ambition and innovation, before turning to the future—AI, automation, democracy, and what human flourishing could realistically look like in a rapidly changing world. Thought-provoking, nuanced, and deliberately uncomfortable at times, this episode invites listeners to think beyond headlines and engage with the deeper patterns shaping our collective future.

What You'll Learn:
How economic, cultural, and demographic forces are shaping the decline of Europe

Why American optimism and mobility continue to drive innovation and growth

How identity, culture, and national values influence political movements

The real impact of immigration on economies, integration, and social cohesion

Why personality, genetics, and openness play a role in ambition and success

How multiculturalism works and where it breaks down in practice

What human flourishing looks like in an unequal and rapidly changing world

Whether democracy can survive technological disruption and AI

⏱ Timestamps
00:00 Intro
03:38 Is the Fifth European Empire Collapsing?
05:40 What “Make America Great Again” Really Looks Back To
06:56 Does the US Have an Identity Crisis?
08:30 Why Optimism Still Separates America From Europe
13:38 Culture, Ambition, and the British Mindset
20:23 Do Personality and Genetics Shape Success?
23:21 Understanding Europe’s Structural Decline
26:49 Why Language and Mobility Matter for Economic Growth
30:33 Why the World’s Top Talent Still Chooses America
32:20 Immigration, Culture, and the Math Behind Integration
34:10 Can Multicultural Societies Truly Coexist?
42:25 What the West Gets Wrong About Cultural Identity
47:13 The Welfare State and Its Long-Term Consequences
49:01 Is Immigration a Net Loss or Net Gain?
52:48 Human Flourishing in a Divided World
55:48 Religion, Secularism, and Shared Values
01:02:32 Separation of Church and State Explained
01:06:31 Gender Equality as a Non-Negotiable Value
01:08:26 The World We’re Headed Toward by 2030
01:10:31 Brexit: A Necessary Risk or Historic Mistake?
01:11:40 What Does Human Flourishing Actually Mean?
01:14:06 Do We Need Struggle to Thrive?
01:15:41 Competition, Conflict, and Progress
01:19:58 When Victimhood Replaces Responsibility
01:23:41 Bias, Fairness, and Modern Power Structures
01:25:19 Is Democracy Dead in the Age of AI?
01:31:58 Technology, Social Media, and Human Nature
01:33:39 Final Reflections on the Future of the West

Connect with Julian
📸 Instagram: @thebeyondtomorrowpodcast
🌐 Website: www.beyondtomorrowpodcast.com
📩 Email: [email protected]
🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Follow Razib:
Website: https://www.razibkhan.com/ 
YouTube: https://www.youtube.com/@razibkhansunsupervisedlearning  
X: https://x.com/razibkhan  
Substack: https://substack.com/@razib 
Razib Khan's Unsupervised Learning Podcast: https://podcasts.apple.com/us/podcast/razib-khans-unsupervised-learning/id1542136715

What if aging is not an inevitable decline but a solvable systems problem hiding in plain sight?

Julian sits down with Carina Kern, a scientist working at the intersection of longevity research and medicine, for a wide ranging conversation on how aging actually works inside the body. Together, they explore why traditional medicine has struggled to address age-related decline and why treating one disease or one organ at a time may be missing the bigger picture. Carina introduces a systems level way of thinking about aging, explaining how cellular damage spreads across the body and why identifying key biological nodes could change how we prevent degeneration altogether. 

Julian and Carina also dive into Carina’s research on necrosis, a form of uncontrolled cell death that may sit at the core of aging and many chronic diseases. Carina explains how her team is developing a first in class anti necrotic therapy, how artificial intelligence is being used to uncover system wide interventions, and why the kidney has become a powerful model for studying accelerated aging. The conversation expands beyond Earth as well, touching on what space travel reveals about rapid aging and why protecting human biology may be essential for the future of human exploration. 

If you want to join the free Beyond Tomorrow Community, check the link: skool.com/beyond-tomorrow for more!  

What You’ll Learn
Why aging is a multifactorial systems problem rather than a single disease

How traditional medicine struggles to treat age related degeneration

What necrosis is and why it may drive aging and chronic illness

How blocking cell death could protect multiple organs at once

The role of AI in discovering longevity therapies

Why longevity research needs scientific rigor over hype

⏱ Timestamps
00:00 Intro
00:27 Linking Longevity and Medicine
02:44 Witnessing a Loved One’s Health Decline
05:17 Introducing the Blueprint Theory
09:03 The Hidden Risks of Unintended Consequences
11:52 Which Hallmarks of Aging Matter Most
18:59 Why Clinical Trials Still Matter
20:48 If You Believe It Works, Prove It
21:47 Inside Anti Necrosis Therapy
26:54 Why the Kidney Matters in Longevity
28:33 Targeting the Root of Degeneration
29:29 Why Necrosis Drives Degenerative Disease
31:06 Building the Right Team Around You
33:27 Can Artificial Intelligence Solve Aging
38:11 Do Astronauts Age Faster in Space
39:29 Why Longevity Is About Interventions
41:16 Preventing Debilitating Health Decline
42:33 Rethinking How We Treat Disease
45:23 How Scalable Is Anti Necrosis Therapy
47:29 Why Longevity Is More Than Wellness
50:38 When Does Necrosis Really Begin
52:03 Is Aging an Engineering Challenge
54:01 Focusing on the End Goal That Matters
55:36 A Vision for the World in 2030
56:17 Where the Longevity Space Is Headed

Connect with Julian
📸 Instagram: @thebeyondtomorrowpodcast
🌐 Website: www.beyondtomorrowpodcast.com
📩 Email: [email protected]
🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Follow Carina:
Instagram: https://www.instagram.com/dr_carinakern  
LinkedIn: https://uk.linkedin.com/in/carina-carla-kern 
YouTube: https://www.youtube.com/@DrCarinaCarlaKern  
X: https://x.com/CarinaCarlaKern 
LinkGevity: https://www.linkgevity.com/