The Beyond Tomorrow Podcast with Julian Issa

Can we really live to 180 or even beyond?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

Dave Asprey believes the future of longevity is arriving much faster than most people realize. He explains why personalized medicine, gene therapies, AI, and biohacking could fundamentally change how we age, and why simply extending healthspan isn't an ambitious enough goal.

From peptides and GLP-1 drugs to creatine, sleep, brain optimization, and nutrition, Dave challenges conventional wisdom on nearly every aspect of health. He argues that the future of medicine won't be based on population averages, but on personalized interventions tailored to each individual's biology.

He also shares why biohacking became a global movement, why embracing calculated risk is essential for progress, and why the biggest breakthrough in longevity may come from giving people greater control over their own health decisions.

Dave Asprey is an entrepreneur, author, and the founder of the biohacking movement. He is the creator of Danger Coffee, a multiple-time bestselling author, and one of the world's leading voices on longevity, cognitive performance, and human optimization.

What You’ll Learn
Why Living to 180 Is Just the Beginning

How Personalized Medicine Is Changing Longevity

The Future of Gene Therapy, Peptides & Biohacking

GLP-1, Creatine & The Next Generation of Health

Why Biohacking Is Becoming a Global Movement

The Biggest Longevity Mistakes Most People Make

⏱ Timestamps
00:00 Intro
00:04 Can You Really Live to 180?
01:46 How Epigenetics Prevents Aging
04:08 Why Taking Risks Extends Life
05:06 The Truth About N=1 Health
07:54 Are Side Effects Overblown?
09:39 Why Biohacking Won
13:26 Biohacking Was Never About Supplements
15:34 Track What You Hack
17:28 Are Peptides Actually Dangerous?
20:10 The Two Minds Controlling Your Body
23:16 Why Governments Should Fund Peptide Research
24:48 Could GLP-1 Slow Aging?
28:09 Why Dave Quit Veganism
30:11 Is Too Much Olive Oil Harmful?
31:42 Is Beef Tallow Actually Healthy?
33:09 The Truth About Creatine
35:01 How Much Creatine Do You Really Need?
36:07 Do You Really Need 8 Hours of Sleep?
39:53 The Best Cognitive Enhancers
41:02 Psychedelics and Human Consciousness
43:50 Can Your Organs Regrow?
47:23 The Future of Stem Cell Therapy
52:45 Is NAD Worth Taking?
54:19 Lessons From Divorce and Co-Parenting
56:17 The Secret to Lasting Happiness
57:48 Choose Your Partner Carefully
59:03 Dave's Long-Term Biohacking Plan
01:00:05 Is Living Forever a Curse?
01:01:37 Does Reincarnation Exist?
01:02:44 Are We Living in a Simulation?
01:05:36 What Psychedelics Really Taught Me
01:06:59 Low-Dose Nicotine for Longevity?
01:08:27 Why You Should Track Yourself
01:10:09 Why Some People Love Pain
01:11:31 The Science of Orgasm and Longevity
01:16:25 The Biggest Longevity Scam
01:17:30 Five Levels of Life Extension
01:21:26 Why Therapy Scares People
01:23:28 The Most Powerful Longevity Habit
01:24:45 Have Humans Stopped Aging?
01:25:54 The Next Longevity Breakthrough
01:28:24 Why Death Gives Life Meaning
01:29:45 The Best Advice Dave Ever Received
01:31:59 If Tomorrow is Your Last Day...

Connect with Dave
Website: https://daveasprey.com/ 
Facebook: https://web.facebook.com/Daveaspreyofficial 
Instagram: https://www.instagram.com/dave.asprey 
TikTok: https://www.tiktok.com/@daveaspreyofficial 
X: https://x.com/daveasprey 
YouTube: https://www.youtube.com/c/DaveAspreyBPR
LinkedIn: https://www.linkedin.com/in/asprey  

Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com

Could AI redefine what it means to be human or put humanity itself at risk?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

As AI races toward AGI, Emad Mostaque explores the biggest questions facing humanity. He explains why the next few years could determine whether AI becomes humanity's greatest tool or its greatest threat.

From the future of work to AI governance, personhood, quantum computing, and longevity, Emad paints a future where intelligence becomes abundant. But he warns that without the right incentives and safeguards, that future could quickly turn dystopian.

He also shares why he believes AGI is much closer than most people expect and why building AI that serves humanity is the most important challenge ahead.

Emad Mostaque is the founder of Intelligent Internet, which is combating corporate tech monopolies and now pioneering decentralized, sovereign, and verifiable AI architectures. He is an Oxford-educated mathematician, former quantitative hedge fund manager and tech entrepreneur who founded Stability AI and launched Stable Diffusion.

What You’ll Learn
Why Emad Thinks AGI Is Only a Few Years Away

The Choice Between AI Abundance and Dystopia

Why AI Should Never Be Granted Personhood

How Decentralized AI Could Protect Humanity

Why AI Could Solve Most Diseases Within a Decade

How Quantum Computing Will Supercharge AI

What the Singularity Means for Humanity

⏱ Timestamps
00:00 Intro
00:11 What It Really Means to Be Human
01:31 Why Systems Always Overoptimize
03:28 Intelligence at the Edge
05:44 Will AI Require a License?
07:34 The AI Duopoly Problem
08:35 Why AI Can't Become a Person
11:23 Can AI Replicate Itself?
15:57 AI Doomers vs Optimists
20:15 How Do We Save Humanity?
21:35 What Should We Teach AI?
25:08 Can Good AI Stop Bad AI?
27:47 AGI vs ASI Explained
30:08 Who Wins the AGI Race?
31:31 Small Changes, Massive Impact
32:52 The Last Human Discoveries
35:01 Can AI Become Conscious?
39:10 What AI Does Better Than Humans
43:09 Why Quantum Changes Everything
44:44 Where to Invest in the AI Era
46:52 Life After ASI
48:50 Will AI Judge Humanity?
51:09 The Inevitable AI Future
53:50 Universal High Income
56:07 Owning AI Instead of Jobs
57:48 The Rise of a Service Economy
01:00:09 Why Human Purpose Will Change
01:01:45 Why Family Matters More Than Ever
01:04:02 Finding Meaning in an AI World
01:06:01 The Value of Human Intelligence
01:07:52 Why Curiosity Still Wins
01:09:49 Be Creative, Embrace Technology
01:12:11 Why Are We Born?
01:13:00 Emad's Best Advice
01:19:16 AI and the End of Work
01:21:48 Ending Human Suffering
01:26:26 A World Run by AI
01:27:49 If Tomorrow is Your Last Day...

Connect with Emad
Website: https://ii.inc/ 
LinkedIn: https://uk.linkedin.com/in/emad-mostaque-9840ba274 
X: https://x.com/EMostaque 

Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

What happens when AI becomes smarter than humanity and are we ready for it?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

The race toward Artificial General Intelligence (AGI) is accelerating faster than most people realize. This conversation explores why some experts believe human-level AGI could arrive within just a few years and why the transition to superintelligence may happen even faster.

Ben Goertzel and Kai Zen Bickle dive into the biggest questions surrounding AGI, recursive self-improvement, and the technological singularity. They debate whether AI should be centralized or decentralized, who should guide its development, and why today's decisions could shape humanity for generations.

Rather than asking whether AGI can be built, the discussion focuses on how it should be built. The episode explores Beneficial General Intelligence (BGI), the importance of ethics, open collaboration, and why creating AI that serves humanity may be the most important challenge of our time.

You can join the 19th Annual AGI Conference, taking place this July in San Francisco! Click the link to register: https://luma.com/AGI-26, and use code JULIAN20 for 20% off your ticket.

About the Guests
Ben Goertzel is an AI researcher, futurist, and CEO of SingularityNET and BGI Labs. Widely recognized as one of the pioneers of Artificial General Intelligence, he has spent more than two decades developing decentralized AI systems designed to benefit humanity.

Kai Zen Bickle is a Chief Ethics Officer at BGI Labs, a multiple award-winning ethics advocate and host of The AGI Race. He works to promote the ethical development of AI, bringing together researchers, entrepreneurs, and policymakers to help ensure advanced AI is built to benefit humanity.

What You’ll Learn
AGI could arrive within years

AGI, ASI, and singularity explained

Why LLMs aren't enough

Centralized vs. decentralized AI

AI ethics before intelligence

AGI's impact on longevity and work

What Beneficial General Intelligence means

⏱ Timestamps
00:00 Intro
00:10 Human-Level AGI Is Near
02:50 AGI vs. Superintelligence
03:33 Recursive Self-Improvement Explained
11:34 The Singularity Explained
13:30 AI Safety Is Failing
17:48 Why We Can't Slow AI
22:42 Why RSI Is Alarming
26:45 Building AI for Humanity
30:04 Can AI Become Conscious?
35:18 The Case for Open AI
39:10 Who Should Control AGI?
43:26 The Longevity Super Pill
50:11 The Purpose Problem
55:42 What Is BGI?
58:34 Every Voice Matters
01:00:39 AI's Moral Constitution
01:07:30 Why Decentralization Matters
01:09:17 Does AI Have a Soul?
01:13:03 Conscious Without a Soul?
01:15:13 Could AI Destroy Humanity?
01:18:34 Inside SingularityNET
01:24:57 What Is OmegaClaw?
01:27:37 BGI Architecture Explained
01:30:54 If Tomorrow Was Your Last Day...

Connect with Ben
Website: https://singularitynet.io/ 
LinkedIn: https://www.linkedin.com/in/bengoertzel 
X: https://x.com/bengoertzel 

Connect with Kai
Website: https://singularitynet.io/

Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is

What’s the biggest problem in longevity today: bad science, hype, or misplaced optimism?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

This debate brings together leading voices in longevity to separate evidence from speculation. They discuss why misinformation is growing and why many people chase advanced treatments before addressing basic health.

The panel explores longevity escape velocity, healthspan versus lifespan, and how much progress has actually been made. They debate whether dramatic life extension is near or still much farther away than many believe.

The conversation also examines peptides, NAD+ infusions, longevity clinics, and biological age tests. Along the way, they discuss risk, regulation, incentives, and how to distinguish credible medicine from marketing.

Get to Know the Guests:
Matt Kaeberlein is a biogerontologist and leading aging researcher known for his work on the biological mechanisms of aging and interventions that promote healthy longevity.

Aubrey de Grey is a biomedical gerontologist and longevity advocate best known for developing strategies to repair age-related cellular damage and accelerate progress toward extending healthy human lifespan.

Dr. Brian Kennedy is a renowned aging researcher and former director of the Centre for Healthy Longevity at the National University of Singapore, focused on translating longevity science into real-world health interventions.

Johannes Weiss is the founder and CEO of Longevity Center Vienna, where he focuses on preventive medicine, root-cause health optimization, and personalized longevity strategies. He is an international speaker and practitioner known for combining longevity science, neurofeedback, and mitochondrial health to improve healthspan.

What You’ll Learn
Why misinformation is growing in longevity

Healthspan vs. lifespan vs. longevity escape velocity

Why health basics matter more than longevity hacks

What the evidence says about peptides and NAD+

How to spot credible longevity clinics

Why biological age tests remain controversial

⏱ Timestamps00:00 Intro
00:48 The Most Dangerous Force in Longevity
02:17 Why Longevity Isn't Medicine Yet
07:23 Why Clinical Trials Still Matter
08:15 The Hidden Bias in Longevity Data
09:40 Can You Make Money in Longevity?
10:34 Fix the Basics First 
11:34 The Risks of Peptide Misuse
16:01 Should Doctors Prescribe Peptides?
17:54 When Optimism Becomes Self-Deception 
26:45 The Myth of Billionaire-Funded Longevity
28:38 The Promise and Risk of Mitochondrial Drugs
31:49 Why Truth Matters in Longevity Science
35:28 Can We Cure All Diseases?
38:55 The Future of Personalized Longevity
42:38 How to Spot a Credible Longevity Clinic
48:02 Peptide Red Flags to Watch For
49:42 The Myth of Longevity Shortcuts
52:33 The Misinformation Problem in Longevity 
58:12 The Most Effective Longevity Drug
01:02:37 If Tomorrow Was Your Last Day...

Connect with Matt
Instagram: https://www.instagram.com/mkaeberlein 
LinkedIn: https://www.linkedin.com/in/mkaeberlein 
X: https://x.com/mkaeberlein 

Connect with Aubrey
Linkedin: https://www.linkedin.com/in/aubrey-de-grey-24260b/
Instagram: https://www.instagram.com/aubreydegrey/
X: https://x.com/aubreydegrey

Connect with Johannes
Website: https://johannesweiss.at/ 
LinkedIn: https://at.linkedin.com/in/johannesweiss-longevity 

Connect with Brian
Website: https://medicine.nus.edu.sg/sites/briankennedylab/ 

Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com

Can AI help us defeat aging or are we still missing the pieces that matter most?

In this episode, Adam and Nathan explore the growing intersection of AI and longevity. They discuss whether accelerating artificial intelligence could unlock breakthroughs in medicine, or if biology remains too complex for current models to solve.

The conversation breaks down the major approaches to extending human lifespan, from cellular replacement and organ engineering to cryopreservation and partial reprogramming. They examine the promises, limitations, and biggest unanswered questions facing the field today.

The episode also dives into the deeper motivations behind longevity research. From the fear of death and the loss of loved ones to the possibility of a future where aging is optional, Adam and Nathan share why they believe extending healthy human life may be one of humanity’s most important challenges.

About the Guests
Adam Gries is the founder and CEO of Vitalism, a nonprofit dedicated to accelerating progress in longevity and human life extension. He is also the creator of Vitalist Bay, a leading gathering that brings together scientists, entrepreneurs, and investors working to solve aging.

Nathan Cheng is the co-founder and CEO of the Longevity Biotech Fellowship. He is a leading advocate for emerging longevity technologies, helping connect researchers, founders, and investors working to extend healthy human lifespan and accelerate progress in rejuvenation biotechnology.

This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com.

What You’ll Learn
Why AI could accelerate longevity research

The most promising approaches to reversing aging

Where current AI tools fall short in biology

Which longevity breakthroughs may arrive first

The opportunities and risks facing the longevity movement

What a future without aging could look like

⏱ Timestamps
00:00 Intro
00:10 AI Could Change Everything
01:16 Most People Misunderstand Longevity
03:28 The Radical Plan to Replace Your Body
07:33 The AI-Longevity Convergence
14:05 Why AI Still Can’t Understand Biology
19:26 The Longevity Gold Rush
22:22 The Next Trillion-Dollar Drug
25:16 The Fear Every Longevity Expert Faces
30:37 The Biggest Myth in Longevity
33:03 When Could Aging Be Solved?
37:36 The Case for Optimism
39:57 The Disaster That Could Set Longevity Back Decades
44:29 A World Without Aging
50:35 What Happens If Death Becomes Optional?
53:11 The Role You Can Play
56:51 Your Race Against Time
01:02:15 If Tomorrow Is Your Last Day...

Follow Adam:
Website: https://vitalismfoundation.org/ 
LinkedIn: https://www.linkedin.com/in/adamgries 
X: https://x.com/adamgries 

Follow Nathan:
Website: https://nathancheng.xyz/ 
Website: https://www.longbiofellowship.org/ 
LinkedIn: https://ca.linkedin.com/in/nathan-cheng-6b464b207 
X: https://x.com/realnathancheng 

Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.