Thyroid Pharmacist Healing Conversations with Dr. Izabella Wentz

In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz interviews functional medicine expert Dr. Sam Shay about the critical lab tests that go beyond TSH for people with Hashimoto’s and hypothyroidism. Dr. Sam shares a pivotal patient story that highlights why “normal” thyroid labs can still leave people suffering – and how a broader, root-cause approach can uncover what’s really driving symptoms.

Together, they discuss thyroid panels, gut permeability and gluten triggers, stress hormones and adrenal patterns, estrogen dominance, nutrient deficiencies, genetics, and the often-overlooked role of mitochondria in fatigue, brain fog, and thyroid-like symptoms.

What you’ll learn in this episode:


Why a “normal” TSH can be misleading – and what a full thyroid panel reveals. Dr. Sam explains how people can have significant thyroid symptoms and autoimmunity even when their TSH is in a “normal” range. He outlines the additional labs that provide a more complete picture of thyroid function, hormone conversion, and immune activity so care is not based on a single number.


How gut permeability and gluten can trigger thyroid antibodies (and why it’s a “two-for-one” problem). Intestinal permeability (“leaky gut”) can allow food particles or microbial byproducts into the bloodstream, prompting antibodies that may cross-react with thyroid tissue. Gluten is a key factor because it can both increase gut permeability and contribute to immune cross-reactivity.


Why chronic stress can suppress thyroid function: Dr. Sam breaks down how HPA axis dysfunction shifts the body into a survival state, which can reduce thyroid activity and slow long-term healing. He also explains how ongoing stress can worsen gut health, creating interconnected challenges.


The role of mitochondria in thyroid-related symptoms. Dr. Sam describes mitochondria as the place where thyroid hormones are activated to produce energy. When mitochondrial function is impaired, individuals may experience symptoms of hypothyroidism even when standard thyroid labs appear normal.


Key symptoms that may point to mitochondrial dysfunction. The discussion highlights patterns such as persistent fatigue, low exercise tolerance, muscle weakness, brain fog, blood sugar instability, and migraines. Dr. Sam also explains how environmental factors like mold and toxins can significantly impact mitochondrial function.


How personalized testing can help identify root causes more effectively. Instead of relying on generalized approaches, Dr. Sam explains how targeted lab testing and genetic insights can guide more precise interventions. This approach helps identify the most impactful changes and can reduce the trial-and-error process often experienced in thyroid care.

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For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/
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In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz interviews integrative psychiatrist Dr. Will Van Derveer about the often-misunderstood field psychedelic-assisted therapy, and how it may be an effective tool for trauma healing and even deeper root cause work. Emphasizing the importance of safety, screening, and in-person clinical support, Dr. Van Derveer discusses the myths and misconceptions about these therapies, how they are very different from recreational drug use, and why they may offer new hope for people dealing with treatment-resistant PTSD depression, and more.

Together, they explore how trauma can shape immune function, inflammation, and even autoimmune conditions. They also discuss EMDR, somatic work, spiritual disconnection, mental health stigma, and the nuanced differences between MDMA, psilocybin, and ketamine in therapeutic settings. While this field is rapidly evolving, he emphasizes that these therapies are not a DIY solution and can be unpredictable or even destabilizing without proper clinical guidance.

What you’ll learn in this episode:


Why psychedelic-assisted therapy is not the same as recreational drug use. Dr. Van Derveer explains that these therapies are used in highly specific clinical settings, with careful screening, preparation, dosing, and follow-up. He also shares why trying to replicate these experiences on your own can be risky, unpredictable, and potentially dangerous, highlighting the critical role of trained practitioners in creating a therapeutic (not recreational) environment.


How unresolved trauma may become an overlooked root cause in chronic illness. Trauma can affect inflammation, immune function, the HPA-axis, and even autoimmune conditions like Hashimoto’s. This is especially relevant for people with thyroid issues, who may have focused only on the physical side of healing while missing an important emotional piece.


Why talk therapy alone may not always be enough. Some people can clearly identify their patterns, understand their trauma intellectually, and still feel stuck. Dr. Van Derveer shares why layered or preverbal trauma may require different approaches, including EMDR, somatic therapies, or psychedelic-assisted therapy, to help people access healing beyond words.


The key differences between MDMA, psilocybin, and ketamine in therapeutic settings. Each therapy has a distinct mechanism, duration, and use case. Dr. Van Derveer breaks down how MDMA is being studied for PTSD, psilocybin for depression, and ketamine for rapid symptom relief, and why clinical MDMA and psilocybin therapy may offer longer-lasting benefits.


Why safety, preparation, and the right practitioner are everything. Dr. Van Derveer explains how improper dosing, lack of preparation, or the wrong environment can overwhelm the nervous system – while skilled guidance can support meaningful and lasting healing.


How trauma healing may improve thyroid antibodies and autoimmune flares. While psychedelic-assisted therapy is not a magic bullet, Dr. Van Derveer has observed improvements not only in mental health symptoms, but also in markers like thyroid antibodies and autoimmune flare frequency, reinforcing the deep connection between emotional and immune health.

Tune in to learn more about trauma, safety, and the evolving role of psychedelic-assisted therapy in root-cause healing.

Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode!

Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: ⁠https://thyroidpharmacist.com/gift/⁠ 

For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: ⁠https://thyroidpharmacist.com/articles/podcast/
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In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz speaks with Sara Russell, PhD, FNTP, a functional nutritional therapy practitioner specializing in women’s mental health and perinatal lab interpretation. Together, they explore the often-missed connections between bipolar symptoms, thyroid dysfunction and autoimmunity, gluten-related disorders (including serum-negative celiac), medication side effects, and postpartum mental health risks.

They also discuss why many patients aren’t properly monitored when prescribed medications like lithium, how blood sugar instability can amplify anxiety and immune activation, and what key labs can help uncover root causes – especially during preconception, pregnancy, and postpartum, when “normal” reference ranges can shift dramatically.

What you’ll learn in this episode:


Why bipolar symptoms can sometimes point to an underlying thyroid issue. Sara explains how hypo- and hyperthyroidism can mimic depression, mania, anxiety, and even psychosis – and why skipping a full thyroid panel (including antibodies) can lead to years of misdiagnosis or mistreatment.


The overlooked triad: thyroid autoimmunity, gluten-related disorders, and psychiatric symptoms. We discuss how celiac disease (including serum-negative celiac) can fly under the radar, how gluten exposure has been linked to neuropsychiatric symptoms in some cases, and why “negative antibodies” don’t always mean “not celiac.”


How the “gluten-free junk food” trap can backfire – especially for mood and antibodies. Dr. Wentz shares her own experience of feeling better off gluten… yet more anxious when her blood sugar swings got worse. We’ll unpack why blood sugar balance can be a game-changer for calm, stable energy, and better immune resilience.


Why lithium requires closer monitoring than many patients receive. Why lithium requires thyroid and kidney monitoring (and why it often doesn’t happen), the “prescribing cascade,” and how one missed lab can snowball into multiple medications and side effects.


The postpartum “gray zone”: bipolar vs postpartum thyroiditis vs autoimmune shifts. Sara shares why postpartum psychosis risk skyrockets in people with bipolar disorder, and why postpartum thyroid changes can muddy the clinical picture – making screening and lab literacy critical in pregnancy and postpartum.


Preconception + pregnancy labs aren’t “one-size-fits-all.” Sara explains how pregnancy changes kidney filtration, thyroid physiology, and reference ranges for many markers, and why interpreting labs by trimester (and postpartum) can prevent unnecessary panic and missed issues.

Tune in to learn how to advocate for the right labs, the right monitoring, and the right root-cause approach, especially when mental health symptoms may actually be driven by thyroid, immune, or metabolic imbalances.

Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode!

Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: ⁠https://thyroidpharmacist.com/gift/⁠ 

For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: ⁠https://thyroidpharmacist.com/articles/podcast/⁠
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In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz explores a surprising perspective on food sensitivities – and why eliminating foods may not actually solve the root problem.

While elimination diets can provide short-term relief for symptoms like bloating, migraines, IBS, and fatigue, Dr. Wentz explains that reacting to multiple foods is often a sign of deeper issues such as gut infections, digestive enzyme deficiencies, microbial imbalances, and intestinal permeability. She shares insights from her own healing journey and outlines the hidden root causes that can drive food sensitivities.

Dr. Wentz also walks through common categories of food reactions – including histamine intolerance, sulfur sensitivity, oxalate issues, and FODMAP reactions – and explains how addressing the underlying gut imbalances can often restore tolerance to many foods.

What you’ll learn in this episode:


Why food sensitivities are often a symptom – not the root cause – of chronic illness. While elimination diets can temporarily reduce symptoms, reacting to dozens of foods is usually a sign of deeper issues like intestinal permeability, gut infections, or immune dysregulation rather than the foods themselves.


How gut infections like Blastocystis hominis can drive food reactions and IBS symptoms. This common protozoal infection may be present in up to 73 percent of people with IBS (according to various studies) and can trigger sensitivities to foods like sugar, wheat, dairy, and fruit until the infection is properly treated.


The hidden digestive deficiencies that can make healthy foods feel intolerable. Issues like low pancreatic enzymes, bile acid deficiencies, or poor fat digestion can lead to symptoms after eating fatty foods and may indicate the need for digestive support rather than eliminating those foods entirely.


Why reactions to sulfur foods, histamine foods, or FODMAPs often signal metabolic or gut imbalances. Sensitivities to foods like garlic, onions, fermented foods, or cruciferous vegetables may indicate nutrient deficiencies or microbial overgrowth rather than true intolerance.


How oxalate and salicylate sensitivities can develop – and what actually resolves them. These reactions are frequently linked to issues like mold exposure, Candida overgrowth, or nutrient deficiencies, rather than the foods themselves.


The supplements and gut-support strategies that can help restore food tolerance. Supporting digestive enzymes, microbial balance, intestinal lining repair, and nutrient status can help many people gradually reintroduce foods they once reacted to.

Tune in to learn how addressing the root causes of gut dysfunction may help you expand your diet and restore your health.

Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode!

Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/ 

For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/
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In this solo episode of the Thyroid Pharmacist Healing Conversations podcast, Dr. Izabella Wentz explains why IBS (irritable bowel syndrome) is often a “wastebasket diagnosis” – a label based on symptoms, not causes. Drawing from her personal healing journey and years of clinical experience, she breaks down why most IBS cases have identifiable, treatable root causes, and how a functional medicine approach can lead to lasting resolution.

Dr. Wentz also introduces her new book, IBS: Finding and Treating the Root Cause of Irritable Bowel Syndrome, a comprehensive guide to uncovering what’s really driving digestive symptoms and addressing them at the source.

What you’ll learn in this episode:


Why IBS is a diagnosis of exclusion, not a root cause: IBS is diagnosed using the Rome IV criteria based on symptoms alone, without identifying what is driving them. Research suggests that up to 98% of people labeled with IBS have a treatable underlying cause. When you investigate the why behind symptoms, healing becomes possible.


The conditions that are commonly mislabeled as IBS: SIBO, bile acid malabsorption, pancreatic insufficiency, celiac disease, carbohydrate intolerances, infections, and even inflammatory bowel disease can all present as IBS. Each requires a different treatment approach, which is why proper identification matters.


Why the low FODMAP diet is not a long-term solution: Although it may temporarily reduce bloating and discomfort, the low FODMAP diet does not address the underlying cause. Long-term restriction may even reduce microbial diversity and worsen gut health if deeper imbalances are not corrected.


How medications can contribute to digestive symptoms: Proton pump inhibitors, pain relievers, and certain drospirenone-containing birth control pills can alter stomach acid, gut motility, and microbial balance. Medication side effects are often an overlooked contributor to IBS symptoms.


The nutrient deficiencies and infections that drive symptoms: Low magnesium, glutamine, zinc, vitamin D, thiamine, and carnitine can impair digestive function. Pathogens such as Blastocystis hominis and Giardia are also frequently found in people with IBS and may resolve symptoms when properly treated.


Why IBS can precede autoimmune disease: Gut dysfunction can appear 5 to 15 years before a diagnosis such as Hashimoto’s. Addressing IBS early may help calm immune imbalance and reduce the risk of progression.

Tune in to learn how to uncover the true cause of your IBS symptoms and take control of your healing journey.

Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode!

Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/ 

For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/

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