Midlife health, perimenopause symptoms, anxiety, sleep issues, burnout and hormone imbalance — why women in their 40s feel “off” even when tests are normal.
In this episode of The Forties Formula, hosts Jasmin Dhillon and Amanda Lim sit down with Dr Olivia Lesslar to unpack why so many women in their 40s feel like something has shifted in their body — yet struggle to get clear answers.
If you’ve experienced lighter sleep, rising anxiety, unpredictable energy, weight changes, or a sense that your body isn’t responding the way it used to, this conversation connects the dots.
Dr Olivia Lesslar is an Australian medical doctor and an expert in psychoneuroimmunology and longevity medicine. Her work focuses on understanding how stress, hormones, the nervous system, and the immune system interact — particularly when symptoms don’t fit neatly into one diagnosis.
Together, we explore:
• Why “normal” test results don’t always reflect how you feel
• The symptoms women dismiss but shouldn’t
• How perimenopause amplifies stress and reduces resilience • Why your body may be trying to protect you, not work against you
• The impact of modern life on an already overloaded system
• GLP-1 medications, wearables, and the confusion around health trends
• Why self-compassion becomes essential in midlife
Chapters
0:00 Introduction — Why women feel “off” in their 40s
2:00 Why women are under-researched
4:30 When tests are “normal” but symptoms aren’t
8:30 Losing connection to your body and identity
13:00 Your body is trying to protect you 16:00 Ancient biology vs modern life
22:00 GLP-1 medications explained
27:30 Wearables and health anxiety
40:00 HRT and perimenopause conversation
44:00 Why women “fall off” in perimenopause
46:45 Self-compassion and the real shift in midlife
About your hosts
Jasmin Dhillon is an Integrated Health Strategist and Health Coach specialising in gut health, hormone balance and nutrition for women in midlife.
Amanda Lim is a Metabolic Health coach passionate about helping women build strength, resilience and confidence in their 40s and beyond.
Thank you to our sponsors
The Meat Club Use code TFF20 for $20 off your first order
Love Indus Use code TFF for 21% off
Cozy Earth Use code TFF for 21% off
Subscribe and follow The Forties Formula for more conversations that help you feel better, think clearer and live stronger.
Tags: perimenopause, midlife health, hormone imbalance, womens health 40s, anxiety in women, burnout, fatigue, sleep issues, gut health, longevity, psychoneuroimmunology, stress, nervous system, GLP1, HRT, fitness trackers, muscle health