PodcastsHealth & WellnessBryan Johnson Podcast

Bryan Johnson Podcast

Bryan Johnson
Bryan Johnson Podcast
Latest episode

20 episodes

  • Bryan Johnson Podcast

    Psilocybin, LSD & Marijuana: Ranking Drugs for Longevity (Part 2)

    11/9/2025 | 56 mins.
    Should I try shrooms for science? In part two of three of our series investigating drugs for longevity, I’m putting psilocybin, LSD and DMT under the microscope - and revealing some pretty exciting research that connects psychedelics to longer lifespans. We’ll also talk about weed, and what the data says about marijuana for longevity.  

    Study Links:

    Psilocybin for Cancer Patients  

    LSD: Longevity in Worms

    Cannabis Use Disorder Increases Mortality Risk

    Marijuana Increases Epigenetic Aging

    Marijuana’s Impacts on Sleep 

    Improving Sleep with Medical Cannabis

    Hosts:

    Bryan Johnson: Blueprint Founder

    Kate Tolo: Blueprint Co-Founder

    Dr. Mike Mallin: Lead Physician for Bryan Johnson

    Connect: 

    X: https://x.com/bryan_johnson

    YouTube: https://www.youtube.com/@BryanJohnson

    Instagram:  https://www.instagram.com/bryanjohnson  

    TikTok:  https://www.tiktok.com/@_bryan_johnson_

    Chapters: 

    00:00 - Introduction 

    01:52 - First Experiences With Drugs 

    05:42 - Psychedelics in Society 

    13:29 - Psilocybin, LSD & DMT 

    34:35 - Marijuana 

    50:53 - Longevity Rankings
  • Bryan Johnson Podcast

    Ketamine & Cocaine: Ranking Drugs for Longevity (Part 1)

    04/9/2025 | 50 mins.
    Can doing lines help you live longer? That depends on what you’re taking. In this three-part series, I’m ranking drugs based on their ties to longevity, starting with ketamine and cocaine. I tested ketamine on myself to study its impacts on the brain — here’s what we found.  

    Study Links:

    Ketamine’s Effects on Epigenetic Age 

    Extending Ketamine’s Therapeutic Window

    Ibogaine Therapy for PTSD 

    Hosts:

    Bryan Johnson: Blueprint Founder

    Kate Tolo: Blueprint Co-Founder

    Dr. Mike Mallin: Lead Physician for Bryan Johnson

    Connect: 

    X: https://x.com/bryan_johnson

    YouTube: https://www.youtube.com/@BryanJohnson

    Instagram:  https://www.instagram.com/bryanjohnson  

    TikTok:  https://www.tiktok.com/@_bryan_johnson_

    Chapters: 

    00:00 - Introduction 

    03:14 - Social Norms Around Drugs 

    08:59 - Psychedelics as Therapy: Overview 

    10:20 - Cocaine 

    17:15 - Fentanyl Dangers 

    23:27 - Ketamine: Brain Impacts + Longevity 

    41:29 - Measuring The Impacts of Psychedelics  

    47:51 - Longevity Rankings: Cocaine + Ketamine
  • Bryan Johnson Podcast

    Jesse James West on AI, Fitness & Self-Worth

    28/8/2025 | 1h 3 mins.
    Fitness creator Jesse James West is a natural bodybuilder who makes some of the coolest videos on YouTube for over 7 million subscribers. We’re talking about his motto of “stay relentless,” and how he balances work, health and life now that he’s newly married. Plus, he shares about the time that he also had a breakdown in Target - and how it may have saved his life.

    Connect with Bryan: 

    X: https://x.com/bryan_johnson

    YouTube: https://www.youtube.com/@BryanJohnson

    Instagram:  https://www.instagram.com/bryanjohnson  

    TikTok:  https://www.tiktok.com/@_bryan_johnson_

    Connect with Jesse: 

    YouTube: https://www.youtube.com/@JesseJamesWest

    Instagram: https://www.instagram.com/jessejameswest

    TikTok: https://www.tiktok.com/@jessejameswest

    X: https://x.com/jessejameswestt

    Chapters: 

    00:00:00 - Introduction 

    00:01:15 - Finding Work Life Balance

    00:08:32 - Stay Relentless 

    00:11:01 - Jesse’s Darkest Moment + What He Learned  

    00:22:48 - What an AI Future Looks Like 

    00:27:24 - Jesse’s Health Protocol 

    00:34:26 - Longevity, Psychedelics, & Aliens 

    00:44:58 - Married Life + Family Planning 

    00:48:55 - Top Tips for Longevity 

    00:54:02 - Bodybuilding, Steroids, & Healthy Eating 

    00:57:23 - Jet Lag Protocol 

    00:59:32 - Living For Tomorrow = Living Forever 

    01:02:45 - Jesse’s Health Goals
  • Bryan Johnson Podcast

    Don’t ‘Dye’ - Empowering Kids to Understand Health

    14/8/2025 | 39 mins.
    Between synthetic dyes, air pollution, and environmental toxins, kids have a lot of obstacles in the way of their health. I’m reviewing some top offenders (like synthetic dyes and added sugars) and discussing how to empower our kids to make informed choices. 

    Study Links: 

    Synthetic Dyes in Food & Beverages

    HEPA Filters in LA Schools

    US Kids Face Deadlier Odds

    Peanut Allergies & Air Pollution

    Hosts:

    Bryan Johnson: Blueprint Founder

    Kate Tolo: Blueprint Co-Founder

    Dr. Mike Mallin: Lead Physician for Bryan Johnson

    Connect: 

    X: https://x.com/bryan_johnson

    YouTube: https://www.youtube.com/@BryanJohnson

    Instagram:  https://www.instagram.com/bryanjohnson  

    TikTok:  https://www.tiktok.com/@_bryan_johnson_

    Chapters: 

    00:00 - Introduction 

    02:20 - Synthetic Dyes + Added Sugars  

    14:20 - Teaching Kids About Nutrition 

    20:21 - Toxins, Food Allergies, & Air Quality 

    22:42 - Kids Health Protocol 

    24:24 - Screen Time, Social Media & Mental Health 

    26:22 - U.S. Kids Are Dying at Higher Rates

    29:44 - Societal Changes for Better Health

    34:41 - Empowering Kids to Make Healthy Choices
  • Bryan Johnson Podcast

    Nobody Taught You THIS About Sex

    07/8/2025 | 38 mins.
    My team and I looked into the biological effects of eating a*s and choking during sex - here’s what we found. I’m also sharing why I monitor my erections - and why this metric is critical for good health and longevity. 

    Study Links: 

    Choking During Sex 

    Overnight Erections

    Female Erection Cycles 

    Hosts:

    Bryan Johnson: Blueprint Founder

    Kate Tolo: Blueprint Co-Founder

    Dr. Mike Mallin: Lead Physician for Bryan Johnson

    Connect: 

    X: https://x.com/bryan_johnson

    YouTube: https://www.youtube.com/@BryanJohnson

    Instagram:  https://www.instagram.com/bryanjohnson  

    TikTok:  https://www.tiktok.com/@_bryan_johnson_

    Chapters: 

    00:00 - Introduction 

    01:15 - Taboos Around Sex 

    04:50 - Sex is Good For You 

    08:33 - Choking During Sex 

    15:06 - Anilingus (Rimming) 

    22:20 - Sexual Preferences + Microbiome 

    25:25 - Erection Cycles: Male and Female 

    34:38 - We Need More Conversations About Sex

More Health & Wellness podcasts

About Bryan Johnson Podcast

The Bryan Johnson Podcast is ushering in a new era of being human.  In this podcast I am joined by longevity physician Dr. Mike Mallin, my co-founder Kate Tolo, and the occasional guest. We discuss the science-based protocol to help you become your best self. After living in Ecuador for two years among extreme poverty at the age of 21, I returned to the US and devoted my life to making the largest and most meaningful impact on humanity. After selling my company Braintree Venmo for $800 million, I traveled back in time to my 21 year old dreams of doing something impactful for the human race. I wondered if we may be the first generation to not die. I put together a team of 30 medical professionals and built the world’s best health protocol, Blueprint. On this protocol, I became the most biologically measured person in history and achieved the best biomarkers in the world, quantitatively becoming the healthiest person on the planet.  Now is the first time in 2,000 years that a new, globally adopted ideology must emerge. AI is progressing faster than any of us can comprehend, causing us to reexamine everything we think about ourselves, each other, and society. This is now humanity’s to-do list:  Don’t die individually.  Don’t kill each other.  Don’t destroy the planet.  Align AI with Don’t Die. Join us on this journey. New episodes releasing weekly.
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