54. What If High Blood Pressure Is Slowly Killing You?
In today’s episode of Extend, we’re tackling a crucial health issue: high blood pressure. Often called the "silent killer," high blood pressure increases your risk for heart attacks, strokes, kidney disease, and more. But what if you could prevent these risks before they escalate? I’ll break down why measuring your blood pressure at home is far more effective than relying on a single doctor’s visit. You’ll also learn about the SPRINT trial and why keeping your blood pressure at 120/70 can significantly improve long-term health. We’ll explore practical steps to manage high blood pressure, including improving your sleep, reducing stress, optimizing metabolic health, and incorporating strength training. Plus, I’ll discuss how new medications and emerging technologies like continuous blood pressure monitoring are transforming care. This episode is all about prevention and early intervention—two key elements to living a longer, healthier life. If you’ve been ignoring your blood pressure, now’s the time to take control. Tune in! I Also Discuss: Understanding High Blood Pressure As A Silent Killer The Importance Of At-home Blood Pressure Monitoring How The Sprint Trial Revolutionized Blood Pressure Management Effective Lifestyle Changes To Control High Blood Pressure Sources: SPRINT Studyhttps://www.sprinttrial.org Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
--------
12:37
53. Dr. Alok Trivedi: You’re Not Lazy—You’re Wired That Way (Here’s How to Change It)
Ever feel stuck, even when you're doing all the right things? In this episode, Dr. Shah sits down with Dr. Alok Trivedi, also known as Dr. Rewire, to explore how our unresolved traumas, subconscious beliefs, and identity patterns silently shape our health, habits, and happiness. You’ll discover how trauma wires into the nervous system, why mindset work often fails without deeper emotional integration, and how behavioral reprogramming can unlock personal and professional breakthroughs. Dr. Trivedi breaks down the neuroscience of change, helping us understand how to stop repeating old cycles and start rewiring for resilience, clarity, and growth. Whether you’re navigating stress, burnout, or simply ready to evolve, this episode delivers science-backed insights with real-world tools to shift your life from the inside out. Dr. Alok Trivedi is a leading expert in performance psychology, founder of the Rewire system, and has helped thousands reprogram their minds for lasting transformation. We Also Discuss: How trauma silently influences your behavior, health, and identity Why mindset work alone isn’t enough for real transformation The science of “rewiring” your brain to break free from subconscious patterns How emotions get stored in the nervous system—and how to release them Why personalized healing depends on the type of trauma you’ve experienced Real-world strategies to shift out of survival mode and into aligned action Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Alok Trivedi: Website: https://drrewiretest.com/ Instagram: @dr.rewireLinkedIn: Dr. Alok Trivedi Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Books: Wired for Wealth: Unlocking Your Brain for Financial SuccessChasing Success: Lessons in Aligned Performance
--------
1:00:28
52. Dr. Greg Kelly: Stop Wasting Money on Supplements! Here’s What Actually Works…
With shelves full of flashy promises, it’s time to cut through the noise. In this episode, Dr. Shah and Dr. Greg Kelly explore what science actually says about supplements—and what your body truly needs to perform at its best. You’ll learn how nootropics, adaptogens, and probiotics influence brain health, stress resilience, and longevity. Backed by clinical research, Dr. Kelly unpacks the key mechanisms behind compounds that support cognitive performance, neuroplasticity, and the gut-brain connection—revealing how your microbiome plays a central role in mood, immunity, and energy regulation. Whether you're aiming for sharper focus, better digestion, or long-term health, this episode delivers a practical roadmap to optimize your supplement strategy—minus the hype. Dr. Greg Kelly is a licensed naturopathic physician and leading authority in nootropics and human optimization. He’s the Director of Product Development at Neurohacker Collective and author of Shape Shift. We Also Discuss: The overwhelming number of supplements on the market How to optimize brain health and performance with the right compounds Enhancing resilience with supplements The link between nootropics and gut health How symbiotics support gut health Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Greg Kelly Instagram: Qualia Life Sciences LinkedIn: Gregory Kelly - Qualia Life Sciences Book: Shape Shift Intelligence Solution Sources: https://www.liebertpub.com/doi/abs/10.1089/acm.2007.7117?journalCode=acm https://www.tandfonline.com/doi/full/10.1080/10408398.2021.2021137 https://www.drashwame.ie/ashwagandha-journal/ashwagandha-lions-mane/ https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1164676/full https://www.mdpi.com/2072-6643/16/22/3955 Thank You To Our Sponsors: Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah
--------
47:53
51. Dr. Navaz Habib: Your Nervous System is Under Attack—Here’s How to Fix It
Inflammation drives nearly every chronic disease, yet most people overlook a key player in regulating it: the vagus nerve. This critical nerve connects brain to body, controlling digestion, heart rate, immunity, and recovery. But chronic stress shuts it down, leading to poor vagal tone, dysregulated inflammation, and reduced resilience. In this episode of Extend, I sit down with Dr. Navaz Habib to explore how vagus nerve activation can reduce inflammation and improve healthspan. We dive into practical strategies to improve vagal tone, from breathwork and cold exposure to high-tech biohacking tools. We also unpack how HRV (heart rate variability) can be your secret weapon for tracking nervous system health, and why it's the future of longevity science. Dr. Navaz Habib is a functional medicine practitioner, speaker, and author specializing in nervous system regulation and inflammation. His work empowers people to take control of their health by optimizing vagal tone and HRV. We Also Talk About: Unlocking Health Through the Vagus Nerve Understanding Chronic Inflammation and Immune Responses Regulating Inflammation Through Vagus Nerve Optimizing Health With Heart Rate Variability Mastering HRV Through Breathwork Exploring Vagus Nerve Health Indicators Exploring Vagus Nerve Stimulation Devices Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Navaz Habib: Instagram: @drnavazhabib Facebook: Dr. Navaz Habib YouTube: Dr. Navaz Habib
--------
1:34:39
50. 50% of Heart Disease Is Diagnosed Too Late—Here’s How to Avoid It
Heart disease is still the number one cause of death, yet most people don’t realize how preventable it actually is. In this solo episode of Extend, I’m kicking off our new series on preventative medicine by breaking down the essential tests and metrics you need to know to protect your heart. I’ll walk you through the four key areas I evaluate in every patient—ischemia, blood pressure, electrical function, and cardiac capacity—and explain how you can assess your own risk starting today. You’ll also learn about the most underutilized tests in cardiology, including the coronary calcium score, CLEARLY CT angiogram, Holter monitors, and VO2 max. These tools can help you detect heart disease decades before symptoms appear—and long before it's too late. This episode is your roadmap to taking control of your cardiovascular health, starting now. If you’re over 40 (or even younger with risk factors), this is a conversation you can’t afford to miss. I Also Discuss: Preventing Heart Disease for Longevity Advanced Heart Health Screening Options Preventing Heart Disease Through Testing The 4 Hidden Heart Risks You Shouldn’t Ignor Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan.
Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results.
That's why this podcast is all about cutting through the noise on how to turn back the aging clock.
I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.
Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
UK