61. Dr. Aly Cohen: The #1 Detox Mistake You’re Probably Making (and What Actually Works)
What if the hidden toxins in your everyday life are secretly sabotaging your health, hormones, and longevity? Most people underestimate how deeply their health is impacted by toxins—and conventional medicine isn’t addressing the root of the issue. In this episode of Extend, I'm joined by Dr. Aly Cohen, renowned integrative rheumatologist, environmental health expert, and author of the upcoming book, Detoxify. We uncover the shocking truth about the tens of thousands of unregulated chemicals lurking in your home, food, water, and even your skincare products—and reveal why detox isn’t about trendy cleanses, but smarter daily choices. We dive into why microplastics have infiltrated every part of your body (including your brain), how seemingly innocent products are disrupting your hormones, metabolism, and immune system, and what practical steps you can immediately take to dramatically reduce your toxic exposure. Dr. Cohen shares eye-opening facts on why your tap water is more polluted than you think, why household dust is toxic waste in disguise, and how simple nutritional strategies can powerfully protect you from environmental harm. We Also Discuss: Detox Myths That Even Most Doctors Believe The Shocking Truth About How Toxins Sabotage Your Immune System Easy Daily Habits to Dramatically Reduce Your Toxic Load Why Reverse Osmosis Is a Non-Negotiable for Your Health Practical Tips to Navigate a Toxin-Free Lifestyle (Without Stress) Hidden Sources of Microplastics You Use Every Single Day Detox Done Right: Supporting Your Liver & Kidneys Naturally The "Four A’s" Method to Protect Your Health from Hidden Chemicals Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Aly Cohen: Website: www.alycohenmd.com Instagram: @TheSmartHuman
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60. Cholesterol Myths You Still Believe (And What to Track Instead)
In this episode of Extend, we’re rethinking everything you’ve been told about cholesterol. For decades, the focus has been on lowering LDL, but that’s only part of the story. The truth? LDL and total cholesterol are outdated metrics. If you're still relying on those alone to assess your heart health, you’re missing the bigger picture. I’ll break down why ApoB is the single most important number to track when it comes to cardiovascular disease, and how it gives a much clearer view of your real risk. You’ll learn how plaque forms, why inflammation and metabolic dysfunction matter just as much as cholesterol, and how to approach your heart health with precision. I'll also cover how to lower ApoB naturally, when medication might make sense, and how advanced scans like CLEARLY can help guide your strategy. ➡️If longevity is your goal, this episode is a must-listen. Let’s move beyond outdated labs and into next-gen heart prevention. I Also Discuss: Why LDL Is Outdated (And What to Track Instead) The Real Cause of Plaque in Your Arteries ApoB: The #1 Biomarker for Heart Health How to Lower Cholesterol Without Statins The Longevity Approach to Cardiovascular Disease Thank you for our Sponsors: Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
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59. Joel Greene: The Nutrition Secret That Reverses Fatigue and Brain Fog
What if the secret to better energy, fat loss, and gut health wasn’t more discipline… but a smarter strategy? Most people are hacking the wrong system—and it’s backfiring. In this episode of Extend, I’m joined by Joel Greene, creator of the VEEP Nutrition System and one of the most innovative minds in metabolic health. We break down the science behind fat loss, blood sugar regulation, gut health, and why conventional diet advice is failing most people. We dive into how your microbiome controls more than just digestion, why fasting isn’t one-size-fits-all, and what your body really needs to burn fat and build lasting energy. Joel also shares cutting-edge insights on short-chain fatty acids, protein misconceptions, and how your environment is silently shaping your metabolic function. If you want to understand how your body actually works—and how to fuel it for longevity and performance—this conversation is a game-changer. We Also Discuss: How the Wellness Industry Got It All Wrong The Hidden Link Between Poor Sleep and Your Diet From Sick to Superhuman: Joel’s Radical Health Turnaround The Forgotten Foods That Heal Your Gut Why Most Gut Protocols Fail (And What to Do Instead) Think You’re Eating Healthy? Think Again. The Missing Piece in Every Metabolic Plan It’s Not Just What You Eat—It’s When and How Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Joel Greene: Website: https://www.veepnutrition.com/ Instagram: https://www.instagram.com/realjoelgreene/?hl=en
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58. Ricky Silver: What the Food Companies Don’t Want You to Know
What if our food system wasn’t designed for our health, but for shelf life, convenience, and corporate profit? In today’s episode of Extend, I’m joined by Ricky Silver, CEO of Daily Harvest, who brings a rare inside-the-industry view of how our food system really works, and how we can change it. We explore how government subsidies, processed foods, and industrial farming practices have led to the chronic disease crisis we’re facing today. We dig into why frozen organic produce is a nutritional powerhouse, what regenerative agriculture actually means, and how everyday consumers like you and me can help shift the food industry toward something more nourishing, for people and the planet. Whether you're someone who shops organic or you're just beginning to question what’s really in your food, this episode will empower you to make smarter choices and push for systemic change. Ricky Silver is the CEO of Daily Harvest, a company focused on making organic, plant-based meals accessible and convenient. He brings a unique perspective on the intersection of science, food, and health. Let’s get into it. We Also Discuss: Why “Organic” Isn’t Just a Label—It’s a System Shift How Your Grocery Cart Can Change the Food Industry The Real Reason Our Food Is Making Us Sick From Profit to Purpose: Rethinking the Food System’s North Star What Farmers Really Want—and Why We Should Listen The Untold Truth About Gluten, Glyphosate, and Gut Health Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Ricky Silver: Website: https://www.dailyharvest.com Instagram: @dailyharvestInstagram: @rickyjsilver
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57. Shawn Wells: Shocking Truth About Supplements: Most Are Useless
What if the reason your supplements aren’t working has nothing to do with your body—and everything to do with what’s in the bottle? In this episode of Extend, I’m joined by biochemist and ingredient formulator Shawn Wells, a leading voice in evidence-based supplementation and mitochondrial health. Together, we uncover why so many products fail to deliver results, how to build a smarter, personalized stack, and what most people get completely wrong about vitamins, probiotics, and biohacking. We get into the dangers of proprietary blends, why over 80% of supplements on Amazon may be underdosed or inactive, and what blood tests and wearables really reveal about your health. Shawn also shares his foundational stack—from GLP-1 agonists to mitochondrial protectors—and explains why dosing and timing matter more than you think. If you’re relying on guesswork when it comes to supplements, this episode will change your approach for good. We Also Discuss: The Supplement Lies You’ve Been Told Why Bio-Individuality Changes Everything How to Spot a Scam Supplement The Foundational Stack You Actually Need Muscle, Brain & Bone: The Smart Stack Upgrade Your Brain: Next-Gen Nootropics The New Science of Sleep Support Immunity, Mitochondria & Microbiome Hacks Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Shawn Wells Website: www.shawnwells.com Instagram: @shawnwells YouTube: Shawn Wells
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan.
Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results.
That's why this podcast is all about cutting through the noise on how to turn back the aging clock.
I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.
Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
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