Everyday Wellness: Midlife Hormones, Health, and Science for Women 35+

• Ep. 497 Masterclass: Testing, Treatment & T3 Truths Revealed with Cynthia Thurlow, NP

  We have the next episode in our series of thyroid-focused podcasts today. In this episode, Dr. Shawn Tassone, Dr. Alan Christianson, and Dr. Amie Hornaman join me to dive into medications, treatment options, personal preferences, and the fear that often drives medical decision-making. We discuss the current prevalence of thyroid-related conditions and why iodine remains a controversial topic in thyroid physiology. We also cover the role of micronutrients and the impact and symptoms of hypothyroidism, clarifying the concept of thyroid pause, and the specific lab tests required for evaluation, in addition to sharing some practical strategies.  Dr. Shawn Tassone advocates for a personalized approach to thyroid treatment, often preferring desiccated or compounded medications over standard synthetics, depending on patient response, insurance coverage, and symptom relief. He also addresses the ongoing resistance within conventional endocrinology to T3-based therapies, despite clear clinical improvements in patients using them. Dr. Alan Christianson explains that the dramatic rise in thyroid disorders over recent decades is due to increased iodine exposure, particularly from processed foods, dairy, supplements, and cosmetics. While iodine is essential for thyroid function, even small excesses can overwhelm the system, triggering autoimmune responses. However, reducing iodine intake can significantly improve or even reverse thyroid dysfunction in many people. Dr. Amie Hornaman explains that optimal thyroid function is essential for overall health, and the active thyroid hormone, T3, is needed by every cell in the body. She highlights the importance of comprehensive thyroid testing to detect dysfunction often missed by standard TSH tests, particularly in women over 40 or those experiencing symptoms linked to perimenopause, menopause, or Hashimoto’s. This enlightening conversation, with three leading thyroid authorities, is packed with valuable insights, so you should revisit it more than once. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. Shawn Tassone On his website Instagram (Appointments: drshawntassone) Call Dr. Tassone’s office: 512 956029 Facebook Connect with Dr. Alan Christianson On his website Facebook, Instagram, Pinterest, and YouTube Connect with Dr. Amie Hornaman On her website Facebook and Instagram YouTube The Thyroid Fixer Podcast Ep 243 Balancing your hormones and thyroid health with Dr. Shawn Tassone Ep. 154 Thyroid & Intermittent Fasting Reset: How to Normalize Your Thyroid Function with Dr. Alan Christianson Ep. 426 Thyroid Health Masterclass: Labs, Diets & Autoimmune Insights with Dr. Amie Hornaman (DCN)

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• BONUS: Muscle Matters: Transforming Metabolic Health for Weight Control with Bronson Dant

  I am happy to connect with Coach Bronson Dant today. He has spent over a decade guiding and training people in health and fitness. He discovered the benefits of a whole-food, animal-based ketogenic diet for optimizing metabolic health and performance, and wrote The Ultimate Ketogenic Fitness Book. In our discussion today, we dive into the powerful story of Coach Bronson’s pain-to-purpose journey. We explore the value of mindset and examine how age-related changes impact muscle, inflammation, and metabolic flexibility. He shares his three pillars of muscle health related to nutrient density, bioavailability, and satiety, and we examine the importance of sleep, the impact of extremes in exercise, and the value of stress management. We also unravel the complexities of weight loss resistance, and Coach Bronson discusses his research from the Journal of Nutrition Metabolism and Health Science, sharing his perspective on macros and functional movement in menopausal women. IN THIS EPISODE YOU WILL LEARN: Coach Bronson shares his three pillars for nutrition The limitations of basing nutrition on calories alone How the hormone piece impacts effective weight management How to avoid physical deterioration through fitness and nutrition Why Coach Bronson advocates for living life to the fullest and dying quickly How does muscle mass impact metabolic health? The importance of taking a balanced approach to weight loss How sleep aids muscle recovery and growth  Stress management, nutrition, and fitness for overall well-being How alcohol affects our health and fitness The benefits of combining functional movement training and proper nutrition for older adults  Connect with Cynthia Thurlow Follow on X, ⁠Instagram⁠ & ⁠LinkedIn⁠ Check out Cynthia’s ⁠website⁠ Submit your questions to [email protected] Connect with Bronson Dant On his ⁠website⁠  ⁠YouTube⁠ and ⁠Instagram⁠ ⁠The Ultimate Ketogenic Fitness Bundle⁠

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• Ep. 496 We Got Brain Health All Wrong – The Shocking Link Between Inflammation, Stress & Aging with Dr. Austin Perlmutter

  Today, I am thrilled to connect with Dr. Austin Perlmutter, a board-certified internal medicine physician, New York Times bestselling author, researcher, educator, podcaster, and entrepreneur. He is on a mission to help people get their brains unstuck for better mental and cognitive health.  In our conversation today, we explore brain inflammation and its connection to longevity, the differences between acute and chronic inflammation, the influence of environmental factors, and how exposure to negative news and biases can elevate stress and affect our brain health. We examine how consumer culture promotes stress and disconnection, and we unpack the immune-metabolic effects of estrogen and its impact on neuroplasticity and our ability to learn. We also focus on the role of nutrition and nutraceuticals, and we discuss the relationship between the brain, gut, and the vagus nerve. This discussion with Dr. Austin Perlmutter is rich and insightful, and I look forward to welcoming him back for further exploration into the science and research. IN THIS EPISODE, YOU WILL LEARN: Why brain inflammation becomes an issue for many women as they navigate middle age and beyond How inflammation leads to constant changes in our cognitive and mental state Various environmental factors and other inputs that could influence brain inflammation Some easy ways to positively impact your brain health and cognition How chronic stress affects the brain How the gut microbiome and the gut immune system influence cognitive and mental health The long-term health benefits of avoiding processed foods and following a Mediterranean diet  The importance of being conscientious and purposeful about the quality of the foods you eat Dr. Perlmutter shares easy and cost-effective ways to improve your cognitive, mental, and overall health Bio: Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, published researcher, and a leading expert on how lifestyle and environmental factors impact mental health. His mission is to help people reclaim their mental and physical health by addressing the biological basis of “stuckness” that disrupts brain function and emotional balance. He is a co-producer of the Alzheimer’s: The Science of Prevention series and the host of the Better Brain Blueprint series, where he provides actionable strategies to support brain resilience. Dr. Perlmutter currently serves as the Managing Director at Big Bold Health, a food-as-medicine company focused on helping people rejuvenate health through better immune function, where he has published a pioneering study exploring the effects of plant nutrients on human aging through epigenetics. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. Austin Perlmutter On his website On social media: @draustinperlmutter Find out more about the research on immuno-metabolism pathways  Big Bold Health on social media: @bigboldhealth

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• 495: Are You At Risk for Dementia? The Most Overlooked Cholesterol Marker You Need to Know with Dr. Thomas Dayspring

  We have the second episode in a series of conversations with Dr. Thomas Dayspring today.  The esteemed Dr. Dayspring is an expert on internal medicine and clinical lipidology. In this episode, we continue with our last conversation, diving into Lp(a) and the influences of gender, race, and menopause. We explain how estrogen is a PCSK9 inhibitor and explore the significance of brain health and risks for dementia. We tackle cholesterol synthesis and discuss the side effects of statins, clarifying who is most susceptible to their impact on the brain. We also examine the significance of the desmosterol biomarker, highlighting the level to aim for, especially when making decisions regarding cholesterol medications, and we answer one question from a listener.  You may want to listen to this insightful conversation with the renowned Dr. Dayspring more than once. He has graciously agreed to return and film additional episodes, where we will dive into more questions from listeners.  IN THIS EPISODE, YOU WILL LEARN: Why Lp(a) is like a wolf in sheep's clothing for many individuals How Lp(a) levels are higher in African Americans and women, especially after menopause  Dr. Dayspring highlights that Lp(a) particles are even more pro-inflammatory than LDL particles How PCSK9 inhibitors are the only drugs that significantly reduce Lp(a) Why do women have a higher risk of dementia than men? Dr. Dayspring explains ApoE as the key lipoprotein for brain cholesterol transport. How statins cross the blood-brain barrier to lower brain cholesterol Why desmosterol levels matter New therapies that can lower ApoB and Lp(a) Why imaging is essential for menopausal women with elevated ApoB and Lp(a) Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. Thomas Dayspring On X (@Drlipid) On LinkedIn Journal Article: Atherosclerosis: Non-genetic influences on lipoprotein(a) concentrations  Journal of the American Heart Association: Trajectories of Blood Lipid Profiles in Midlife Women: Does Menopause Matter?

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• BONUS: Think You’re Getting Enough Protein? – The Shocking Truth About Amino Acids & Aging with Angelo Keely

  We have another episode in our series of sponsored podcasts today, with brands I like, know, and trust. I am delighted to reconnect with Angelo Keely, the founder and CEO of Kion, a supplement company that focuses on helping people look good, feel young, and be strong. In our discussion today, Angelo explains essential aminos, highlighting their importance and clarifying how to differentiate between various protein powders and other forms of protein. We explore the significance of bioavailability, anabolic resistance, and changes in body composition, discussing how protein needs increase with age and how dieting and caloric restriction can augment our protein requirements. We also cover the results of intermittent fasting, examining how sleep, stress, and lifestyle requirements can change with menopause. I regularly take Kion essential amino acids. They have generously offered a discount for our community. Use the link in the show notes to get 20% off your next Kion purchase. IN THIS EPISODE, YOU WILL LEARN: The importance of eating sufficient protein as you age How various protein sources, such as animal protein, plant protein, whey protein, and essential amino acids, differ Strategies to buffer your protein intake and support your body as you navigate middle age and beyond Why Leucine is vital for muscle protein synthesis Why you should only source your amino acid supplements from trusted brands that follow the science How much protein do you need to maintain your body composition as you age? Why sleep is crucial for muscle protein synthesis How supplementing with essential amino acids helps you maintain your muscle mass throughout your life   The benefits of body scans for a better understanding of your body composition Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Angelo Keely Get a 20% discount on Kion products

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