The Dr. Tyna Show

In this episode, I'm breaking down the difference between lean mass loss and actual muscle loss, where the widely repeated “40% muscle loss” claim came from, and what the latest research really shows. I also dive into metabolic dysfunction, fatty infiltrated muscle, anabolic resistance, strength training, protein intake, and why muscle quality matters far more than most people realize.

If you've been worried about losing muscle on a GLP-1, are currently taking one, or simply want to better understand the science behind weight loss, body composition, and long-term health, this episode is for you.

Topics Discussed:

→ Do GLP-1s Actually Cause Muscle Loss?

→ The Truth About Lean Mass vs Muscle Mass

→ Where The 40% Muscle Loss Myth Came From

→ Why Metabolic Health Matters For Muscle

→ How To Preserve Muscle While Losing Weight

→ Why Strength Training Is Non-Negotiable

→ Protein, Aging & Anabolic Resistance

→ What The Newest GLP-1 Studies Reveal

Sponsored By:

→ Sunlighten | Learn more at https://sunlighten.com/drtyna and use code DRTYNASHOW to save up to $2,100 and get free shipping with your sauna purchase.

→ Timeline | Timeline’s clinically proven formula is now available at a new, lower price. Mitopure now starts at $79, when you go to https://timeline.com/drtyna

→ Cheers | For a limited time our listeners are getting 20% off their entire order at https://CheersHealth.com/DRTYNA #Cheers #ad

→ ENERGYbits | Fuel your body with ENERGYbits, single-ingredient spirulina & chlorella superfoods. Just $1/day when you use code DTS for 20% off at https://ENERGYbits.com

→ Sundays | Make the switch to Sundays. Go right now to https://sundaysfordogs.com/DRTYNA50 and get 50% off your first order. Or, you can use code DRTYNA50 at checkout.

→ BIOptimizers | For an exclusive offer, go to https://bioptimizers.com/drtyna and use code DRTYNA for 15% off + a FREE MassZymes bottle. Limited time, while supplies last.

→ Puori | Go to https://puori.com/DRTYNA and use the code DRTYNA at checkout to get 32% off your first Puori Grass-fed Whey Protein subscription order and get a free premium shaker bottle.

→ Sunlighten | Learn more at https://sunlighten.com/drtyna and use code DRTYNASHOW to save up to $2,100 and get free shipping with your sauna purchase.On This Episode We Cover:

→ 00:00:00 - Introduction

→ 00:01:18 - The 40% Muscle Loss Myth

→ 00:03:27 - Pathologic Muscle + Metabolic Dysfunction

→ 00:06:35 - Why GLP-1s Are Being Misunderstood

→ 00:09:18 - Why Strength Training Is Non-Negotiable

→ 00:15:15 - Lean Mass vs Muscle Mass

→ 00:16:15 - How GLP-1s Affect Inflammation + Immune Health

→ 00:18:12 - How Obesity Damages Muscle Quality

→ 00:19:18 - New Research On GLP-1s + Muscle Function

→ 00:20:57 - Why Muscle Quality Matters More Than Quantity

→ 00:22:48 - How GLP-1s May Remodel Muscle Tissue

→ 00:25:27 - Strength Loss, Weight Loss + Performance

→ 00:27:10 - Bone Density + Weight Loss Concerns

→ 00:28:24 - Building Bone Through Strength Training

→ 00:37:07 - Recovery, Stress + Muscle Preservation

→ 00:38:33 - Sauna Recovery + Sunlighten

→ 00:42:12 - Glutes, Longevity + Metabolic Health

→ 00:48:15 - What The Latest Human Data Shows

→ 00:50:18 - Anabolic Resistance + Aging

→ 00:55:27 - What The Latest Meta-Analysis Shows

→ 00:57:54 - How GLP-1s May Improve Muscle Biology

→ 00:59:42 - Final Takeaways On GLP-1s + Muscle Loss

Studies: 

→ Muscle Loss And Glp-1r Agonists Use

→ Weight Loss With Glp-1 Medicines Does Not Result In A Disproportionate Loss Of Muscle Mass Or Function In Obese Mice And HumansFurther Listening:

→ GLP-1s + Peptides Are Changing Fast, Here’s What You Need To Know

→ EP. 104: Fatty Liver 101 | Solo Episode

→ Orthopedic Medicine is a Scam PT. 3 | Osteoarthritis is Diabetes of the Joint

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

EP. 263: In this episode, I’m joined by Angelo Keely of KION to unpack what actually happens when body composition starts changing in midlife. We get into perimenopause, appetite, GLP-1s, protein, muscle loss, essential amino acids, and why fat loss is not just about “trying harder.” This is a deeper conversation about building muscle, protecting your metabolism, and using the right tools without losing sight of the basics.

→ Visit https://getkion.com/drtyna for 20% off

Topics Discussed:

→ How do GLP-1s affect muscle loss?

→ Why is fat loss harder after 40?

→ Do amino acids help preserve muscle?

→ How much protein do women need?

→ What causes perimenopause weight gain?

Sponsored By:

→ Visit https://getkion.com/drtyna for 20% off

On This Episode We Cover: 

→ 00:00:00 - Introduction 

→ 00:02:05 - HRT, Aging + Body Recomp 

→ 00:08:41- Perimenopause + Metabolism Changes 

→ 00:11:32 - Sleep, Hormones + Muscle Loss

→ 00:14:27 - Habits, Identity + Weight Loss

→ 00:19:43 - Stress, Cortisol + Cravings

→ 00:23:53 - Emotional Eating + Appetite Control

→ 00:27:30 - GLP-1s + Appetite Regulation

→ 00:29:36 - Obesity, Genetics + Hunger Signals

→ 00:32:05 - GLP-1 Stigma + Fat Loss Bias

→ 00:35:44 - Protein, Muscle + Aging

→ 00:40:43 - Essential Amino Acids Explained

→ 00:46:53 - GLP-1s, Lean Mass + Strength Training

→ 00:48:53 - NASA Studies: Amino Acids 

→ 00:52:17 - Hospitalization, Frailty + Muscle Wasting

→ 00:53:44 - Leucine, Protein Synthesis + Recovery

→ 00:56:01 - Diet + Nutrition  

→ 01:01:25 - Amino Acid Timing + Best Practices

→ 01:01:17 - Appetite + Nutrients 

→ 01:09:12 - Creatine + Strength Training 

→ 01:17:13 - Body Recomp + KION Recommendations 

Further Listening: 

→ EP. 87: Amino Acids + Why You Need Them w/ Angelo Keely

→ EP. 147: Strength, Aging, and Amino Acids: Balancing Nutrition for Muscle Preservation-Angelo Keely

Check Out Kion:

→ Visit https://getkion.com/drtyna for 20% off

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

EP. 262: Get it Now: Everything I'm Using To Help My Scalp And Hair Thrive In Perimenopause

Lately I’ve been getting nonstop questions about my hair…what I’m doing, why it’s growing so much, and what changed. The truth is, I completely shifted the way I think about hair health, and it wasn’t what I expected.

In this episode, I’m breaking down the biggest things I believe people are missing when it comes to thinning hair, scalp irritation, stress shedding, hormones, and aging. I also share some of the changes I made personally that had the biggest impact for me.

If you’ve noticed your hair changing, your scalp becoming more sensitive, or you just want healthier hair as you age, this episode is for you.

Topics Discussed:

→ Why does hair thin?

→ Does scalp health affect hair growth?

→ What causes menopause hair loss?

→ Can stress trigger hair shedding?

→ How often should you wash hair?

Sponsored By:

→ ENERGYbits | Fuel your body with ENERGYbits, single-ingredient spirulina & chlorella superfoods. Just $1/day when you use code DTS for 20% off at https://ENERGYbits.com

→ BIOptimizers | For an exclusive offer, go to https://bioptimizers.com/drtyna and use code DRTYNA for 15% off + a FREE MassZymes bottle. Limited time, while supplies last.

→ Sundays | Make the switch to Sundays. Go right now to https://sundaysfordogs.com/DRTYNA50 and get 50% off your first order. Or, you can use code DRTYNA50 at checkout.

→ Timeline | Timeline’s clinically proven formula is now available at a new, lower price. Mitopure now starts at $79, when you go to https://timeline.com/drtyna

→ Puori | Go to https://puori.com/DRTYNA and use the code DRTYNA at checkout to get 32% off your first Protein subscription order and get a free shaker worth $25.

→ Cozy Earth | This spring, give yourself the kind of comfort that lives with you all day — not just the moment you get home. Head to

https://cozyearth.com and use my code DRTYNA for an exclusive 20% off.

On This Episode We Cover: 

→ 00:00:00 - Introduction 

→ 00:04:35 - Metabolic Health + Minoxidil

→ 00:07:49 - PRP Therapy + Dermaroller

→ 00:12:18 - Microneedling Risks + Scalp Health 

→ 00:15:55 - Barrier Integrity 

→ 00:18:43 - Dht (Testosterone) 

→ 00:20:18 - Female Pattern Hair Loss 

→ 00:26:45 - Scalp Routine Overview 

→ 00:28:50 - Dry Your Roots! 

→ 00:31:42 - Moisturizing + Hydration

→ 00:33:55 - Traction Alopecia 

→ 00:35:49 - Scalp Massage 

→ 00:39:39 - Scalp Tension 

→ 00:45:25 - Hormones + HRT 

→ 00:47:10 - Product Recommendations 

→ 00:52:20 - Hair Growth vs Retention 

→ 00:55:54 - Red Light + Laser Caps

→ 00:57:38 - Personal Hair Loss 

Show Links:

→ Everything I'm Using To Help My Scalp And Hair Thrive In Perimenopause

→ Metabolic Revamp Toolkit + Masterclass

→ Strength Vault

→ Substack

Further Listening: 

→ EP. 233 | Hair Loss 101: What Every Woman Needs to Know | Solo

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

EP. 261: Get Strong with Me Inside my NEW Strength Vault: https://www.drtyna.com/offers/G33fSdvS

In this episode, I sit down with Dr. Amy Hornaman to go deep on thyroid dysfunction, Hashimoto’s, and why so many people are misdiagnosed or undertreated. We break down T3 vs T4, reverse T3, molecular mimicry, and how stress, viral triggers, and lifestyle factors can push people over the edge into full thyroid dysfunction. This conversation also covers why lab work alone misses so much and how real thyroid treatment can change energy, mood, pain, and metabolism.

Topics Discussed:

→ What are the signs of hypothyroidism?

→ Why do thyroid labs look normal?

→ What’s the difference between T3 and T4?

→ Can Hashimoto’s cause weight gain?

→ How does stress affect the thyroid?

Sponsored By:

→ BIOptimizers | For an exclusive offer, go to https://bioptimizers.com/drtyna and use code DRTYNA for 15% off + a FREE MassZymes bottle. Limited time, while supplies last.

→ Ogee | Thanks to today’s sponsor, Ogee: A higher standard for beauty. Go to https://ogee.com/DRTYNA and use code DRTYNA to get 15% off certified organic makeup that performs like luxury. 

→ KION | Visit https://getkion.com/drtyna for 20% off

→ Sunlighten | Learn more at https://sunlighten.com/drtyna and use code DRTYNASHOW to save up to $1,400 on your sauna purchase with additional savings throughout the year. 

→ Manukora | Head to https://manukora.com/DRTYNA to save up to 31% plus $25 worth of free gifts with the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook!

On This Episode We Cover: 

→ 00:00:00 - Introduction 

→ 00:01:25 - Dr. Aime’s Hashimoto’s Experience

→ 00:07:42 - Dr. Tyna’s Clinical Experience 

→ 00:13:12 - Thyroid Dysfunction + Depression

→ 00:16:13 - Symptoms Most Doctors Miss 

→ 00:19:39 - Understanding Hypothyroidism 

→ 00:23:40 - Perimenopause, Menopause, + Hormones 

→ 00:25:46 - T3 vs T4: Why Some Treatments Fail

→ 00:31:20 - Thyroid + Immune System

→ 00:34:52 - The Power of Thyroid 

→ 00:37:49 - Thyroid + Epstein-Barr Virus (Mono)

→ 00:38:35 - How Common Is Hashimoto’s?

→ 00:43:05 - Testing + Chronic Illness 

→ 00:47:46 - Long COVID + Viral Load

→ 00:49:09 - Thyroid, HRT + Weight Gain 

→ 00:51:25 - GLP1 Side Effects + Thyroid 

→ 00:55:45 - Lifestyle Changes + Reverse T3 

→ 01:00:38 - Low Thyroid + Cortisol 

→ 01:03:56 - Live Life To The Fullest 

→ 01:05:16 - Dr. Tyna’s Mental Health Journey 

→ 01:09:33 - Prevalence of Hypothyroid

Further Listening: 

→ EP. 91: Thyroid Secrets Your Doctor Doesn't Know | Solo Episode

Check Out Dr. Amie:

→ Website

→ The Thyroid Fix (Book)

→ Instagram

→ YouTube

→ Facebook

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

EP. 260: Get Strong with Me Inside my NEW Strength Vault: https://www.drtyna.com/offers/G33fSdvS

In this episode, I walk through the current state of GLP-1 medications and peptides, including what is changing with compounded access, recent FDA actions, and the shifting roles of 503A and 503B pharmacies. I break down what this means in practical terms for patients and clinicians as availability continues to evolve and brand name pathways become more prominent.

I also cover the broader peptide landscape, including regulatory uncertainty, dosing and safety concerns, and why there is so much confusion in the space right now.

Topics Discussed:

→ What is happening with peptides now?

→ Are peptides safe?

→ Are compounded GLP-1s ending?

→ What is 503A vs 503B?

→ Why are GLP-1s changing?

Sponsored By:

→ LMNT | Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at https://drinklmnt.com/drtyna. Find your favorite LMNT flavor, or share with a friend.

→ Sundays | Make the switch to Sundays. Go right now to https://sundaysfordogs.com/DRTYNA50 and get 50% off your first order. Or, you can use code DRTYNA50 at checkout.

→ Timeline | Timeline’s clinically proven formula is now available at a new, lower price. Mitopure now starts at $79, when you go to https://timeline.com/drtyna

→ Puori | Go to https://puori.com/DRTYNA and use the code DRTYNA at checkout to get 32% off your first Protein subscription order and get a free shaker worth $25.

→ ENERGYbits | Fuel your body with ENERGYbits, single-ingredient spirulina & chlorella superfoods. Just $1/day when you use code DTS for 20% off at https://ENERGYbits.com

On This Episode We Cover:

→ 00:00:00 - Introduction

→ 00:02:41 - 503A + 503B Production Updates

→ 00:06:22 - Individualized Dosing

→ 00:10:03 - Peptide Shortages

→ 00:14:49 - Compounding Pharmacies

→ 00:18:29 - Vial-Based Peptide Options

→ 00:19:58 - Big Pharma, Telemedicine, + Amazon

→ 00:27:39 - Musculoskeletal (MSK) Medicine

→ 00:31:50 - Do Not Compound List

→ 00:33:45 - Grey Market Peptides

→ 00:38:10 - Dosing + Side Effects

→ 00:41:35 - RFK Jr + Joe Rogan

→ 00:43:38 - Influencer Kickbacks

→ 00:47:15 - Peptide Misconceptions

→ 00:50:02 - Peptides, Cancer, + VEGF

→ 00:53:15 - Talk To Your Doctor!

→ 00:56:47 - What’s Next For Peptides

→ 01:00:55 - An Ethical FDA + Lab Reporting

→ 01:04:45 - Peptides + Optimal Health

Show Links: 

→ Metabolic Revamp Toolkit + Masterclass

→ Strength Vault

→ Substack

Further Listening: 

→ The GLP-1 Microdosing Lie: It's NOT a Weight Loss Strategy | Solo EP. 221

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.