Dhru Purohit Show

• How To Catch Heart Disease, Alzheimer’s and Cancer Early: Tests You Need To Know About, Genetic Risk Factors, and Key Lifestyle Habits that Make a Difference with Dr. Eric Topol

  This episode is brought to you by One Skin and Momentous. Cardiovascular disease remains the leading cause of death worldwide. But today, we no longer have to wait for symptoms to understand our risk. Advances in technology now make it possible to get a clear snapshot of individual risk, not only for heart disease, but also for cancer and neurodegenerative conditions, empowering us to take proactive steps to lower risk and support long-term health. Our guest today breaks down what’s truly worth investing in and what we can skip. Today on The Dhru Purohit Show, Dhru sits down with Dr. Eric Topol, a cardiologist and Professor of Molecular Medicine at the Scripps Research Institute. Dr. Topol shares insights on the importance of preventive health, with a focus on cardiovascular disease, cancer, and neurodegenerative conditions. He explains the role of polygenic risk scores in assessing individual risk, explores the strengths and limitations of various testing methods, and highlights how lifestyle choices shape disease prevention. Dhru and Dr. Topol also discuss emerging technologies in health monitoring, the influence of environmental factors like air pollution, and what the future may hold for aging and health management. Dr. Eric Topol is Executive Vice President and Professor of Molecular Medicine at Scripps Research and founder of the Scripps Research Translational Institute. A practicing cardiologist and one of the ten most-cited researchers in medicine, he is renowned for his wor in AI, genomics, and digital clinical trials. Named to the Time 100 Health list in 2024, he also writes the Ground Truths newsletter and is the author of The Creative Destruction of Medicine, The Patient Will See You Now, Deep Medicine, and Super Agers. In this episode, Dhru and Dr. Topol dive into:  Cardiovascular disease causes, risks, and prevention (1:07) Polygenic risk genetic links to disease and understanding your risk (7:56) Heart health with Dr. Topol’s key recommendations (13:21) Cancer testing types of tests and how to approach results (27:47) Medical guidance mistrust, confusion, incidental findings, and the importance of evidence-based practitioners (34:20) Alzheimer’s detection, blood work, testing, and the role of AI (43:13) Environmental risks, air pollution, and sleep irregularity, and why these factors must be addressed (53:20) Parkinson’s disease: the fastest-growing neurodegenerative condition (57:01) Prevention and lowering your risk of developing major diseases (59:52) Gut health and the gut-hormone connection (1:02:05) Aging and immunity: links between age-related diseases and the immune system (1:06:19) Measuring biological age (1:08:14) Final thoughts and takeaways (1:16:27) Also mentioned in this episode: Super Agers: An Evidence-Based Approach to Longevity Polygenic Risk Scores: Ready for Prime Time? What a Polygenic Risk Score Can and Can’t Tell You Allelica Polygenic Risk Test Dhru’s APOE Chat GPT Results  For more on Dr. Topol, follow him on X/Twitter, The Scripps’ socials: X/Twitter, Facebook, Instagram, YouTube, TikTok, Threads, LinkedIn, Bluesky, or visit their Website. This episode is brought to you by One Skin and Momentous. Right now, One Skin is offering my community 15% off; just go to oneskin.co and use the coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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• Is Sauna Use One of the Most Underrated Tools We Have for Reducing Risk of All-Cause Mortality? This Expert Says Yes.

  This episode is brought to you by Branch Basics and Bon Charge. What if you could lower your risk of cardiovascular disease by 69%? Today’s guest reveals how regular sauna usage, one of the most underrated tools for longevity, brain health, and cardiovascular function, can make that possible. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Susanna Søberg on the benefits of consistent sauna use. Dr. Søberg highlights the added impact of pairing sauna with exercise, offers practical tips for adapting to the heat, and shares the latest research showing how sauna use can reduce all-cause mortality and boost nitric oxide production. Dr. Susanna Søberg is one of the world’s leading researchers and experts in cold and heat therapy, as well as functional breathing. She is the founder of the Soeberg Institute, which offers an online, research-backed curriculum designed to help people optimize stress management and performance for a healthier, happier life. Dr. Søberg earned her PhD in metabolism at the University of Copenhagen, where her research advanced our understanding of brown fat metabolism in adults. In this episode, Dhru and Dr. Søberg dive into: The health benefits of regular sauna use (1:27) Pairing sauna with exercise for an extra boost (3:20) How to adapt to heat in the sauna (8:15) Research on sauna use and reducing all-cause mortality (12:37) How the brain responds to sauna (15:34) Sauna and nitric oxide production (18:29) Also mentioned: Full episode with Dr. Susanna Søberg Try This: 2 Fascinating Studies, Sauna Benefits, a Way to Beat Jet Lag, and More Try This: Sauna Bathing for Longevity, Cognition, & Heart Health This episode is brought to you by Branch Basics and Bon Charge.  Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Right now, Bon Charge is offering my community 15% off; just go to boncharge.com/DHRU and use the coupon code DHRU to save 15%. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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• Simple and Safe Evidence-Based Ways to Reduce Autism Risk From a Physician and a Father On a Mission

  This episode is brought to you by BiOptimizers, Birch Living, and Our Place. Autism rates have increased fivefold over the past twenty years. While much remains unknown about how children develop autism, research suggests that the rise in cases may not be explained by increased diagnoses alone. Today’s guest takes us on a deep dive into autism and shares his proposals for reducing these rates. Today on The Dhru Purohit Show, Dhru sits down with Dr. Jeff Zadeh for a deep dive into autism and the research he’s uncovered on key strategies that may reduce the likelihood of a child being diagnosed with autism. While Dr. Jeff acknowledges that much remains unknown about why some children are on the autism spectrum, he highlights the top nutrients and vitamins women should focus on before pregnancy to help lower the risk. From dosages to deficiencies, Dr. Jeff breaks down what the research shows so far. He also shares his personal journey with his son’s diagnosis and what inspired him to begin exploring this topic in depth. Dr. Jeff Zadeh, a board-certified internist with nearly 30 years of experience, founded Dallas Medical Specialists in 2005 and later moved his practice to rural North Texas, where he serves as a hospitalist, trauma director, and emergency physician. After his oldest son was diagnosed with autism, he discovered research suggesting many cases may be preventable through prenatal counseling, yet most physicians were unaware of it. Inspired by this and the work of Dr. David Berger, he wrote Autism Prevention 5 Days a Week to share simple, evidence-based prevention strategies in accessible language. In this episode, Dhru and Dr. Zadeh dive into: Dr. Zadeh’s personal journey with his son’s autism diagnosis (00:55) Dr. Zadeh’s medical background and the challenges of obtaining a diagnosis (8:50) The importance of supplementation before conception (27:32) What to look for in prenatal vitamins (45:27) The 5-day-a-week proposal and the studies behind it (49:55) Maintaining sufficient iron levels in women (1:06:33) Why checking thyroid levels before pregnancy is essential (1:15:21) Environmental toxin exposures affecting pregnancy (1:15:26) The risks of taking Tylenol during pregnancy (1:27:23) The connection between celiac disease and autism (1:31:35) How increasing DHA omega-3 and vitamin D intake may lower the risk of autism (1:35:32) The role of choline in autism prevention (1:51:12) Key factors we should pay attention to (1:54:47) Dr. Zadeh’s reflections as a parent of a child on the autism spectrum (2:00:20) Final thoughts and takeaways (2:07:30) Also mentioned in this episode: Dr. Jeff Zadeh’s Slides Autism Prevention 5 Days a Week Dr. Rhonda Patrick BPA Instagram Post  For more on Dr. Zadeh, follow him on X/Twitter and visit his Website. This episode is brought to you by BiOptimizers, Birch Living, and Our Place. Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU to get 15% off any order and free gifts for a limited time. Get 25% off your Birch Living mattress during their Labor Day Extended Sale—just head to birchliving.com/dhru today!  Reduce your toxic load by upgrading your cookware! Go to fromourplace.com today and use promo code DHRU at checkout to receive 10% off any order. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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• 70% of Homes In the U.S. Have Mold. Here's How to Protect Your Health and Your Home from Toxic Mold

  This episode is brought to you by Pique Life and Branch Basics. Air quality and mold are major factors in overall health and wellness. In fact, 70% of homes in the United States contain at least one species of mold. Exposure can trigger chronic inflammation, fatigue, and brain fog, but with the right knowledge, you can take proactive steps to protect your health. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Michael Rubino to explore how and why mold is so prevalent in most homes and how it can worsen autoimmune disease. Michael breaks down the most common sources of mold people encounter and why the problem is getting worse. He also highlights the four most toxic types of mold and explains how their presence in the body can cause damage through self-preservation mechanisms. Finally, Michael explains why some people are more susceptible to the effects of mold than others. Michael Rubino is the Founder of HomeCleanse, President of the Change the Air Foundation, and host of the Never Been Sicker podcast. A council-certified Mold Remediator with a background in construction, he focuses on helping immunocompromised individuals recover from mold exposure. In this episode, Dhru and Michael dive into: Why mold is the number one toxin found in homes (1:56) The most common sources of mold people encounter (6:11) Why the mold problem is getting worse (7:28) Memorable client stories (13:22) Types of mold to watch out for (18:32) The four most toxic molds (20:08) How mold damages the body through self-preservation mechanisms (24:01) Why some people are more affected by mold than others (26:08) Final thoughts (28:03) Also mentioned: Full episode with Michael Rubino This episode is brought to you by Pique Life and Branch Basics. Right now, Pique Life is offering 20% off their Sun Goddess Matcha. Plus, you’ll get a free beaker and frother when you go to piquelife.com/dhru. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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• The Universe Is Sending You Signs: Are You Listening? How to Fine Tune Your Intuition to Step Into Your Purpose and Dream Life with Dr. Tara Swart

  This episode is brought to you by Cozy Earth, LMNT, and Fatty15. Have you ever had a sign or a gut feeling that you brushed off as a coincidence? What if those moments weren’t random at all, but subtle guidance pointing you in the right direction? On today’s episode, we explore how these signs show up in our lives, why we often miss them, and how understanding the science behind intuition can help us tune in and act with clarity. Today on The Dhru Purohit Show, Dhru sits down with world-renowned neuroscientist Dr. Tara Swart to explore the key signs of greater intelligence that often appear in our lives. She explains how our modern world can prevent us from noticing these signs and receiving guidance, and how the brain itself acts as a filter. Through practices such as visualization and intention-setting, we can activate the reticular activating system to better recognize opportunities that align with our goals. Dr. Tara also breaks down the science of intuition and “signs,” showing how gut feelings and dreams are rooted in real brain-body connections, while offering practical tools to rewire limiting beliefs. She reminds us that transformation isn’t magic, but rather biology combined with aligned action. Dr. Tara Swart is a PhD neuroscientist and Oxford University-trained medical doctor. She is Senior Advisor for Neuroscience and Leadership at MIT Sloan School of Management, best-selling author of The Source, and a Trustee of the Lady Garden Foundation. Tara is the Chief Science Officer at Dirtea, an adaptogenic mushroom company, and the Mind Ambassador at Healf.com. Tara is passionate about empowering people through the intersection of science and spirituality. In this episode, Dhru and Dr. Swart dive into:  Dr. Tara’s personal story of loss, grief, and her journey with signs and patterns (1:10) Fundamental beliefs we accept without proof and a discussion on near-death experiences (7:02) What Dr. Tara realized after her husband’s death and the greater source present in the universe (17:24) The importance of having community (20:17) Dhru’s personal story of signs after loss (21:25) How Dr. Tara navigated her grief and what led her to write her book (38:50) Why sharing your experiences with signs matters and how to identify your own (47:14) Finding a sense of purpose through signs (1:07:00) Practices to help us access and strengthen our intuition (1:18:57) The power of journaling (1:23:21) What to do when you ask for a sign and don’t get one (1:29:56) Feeling connected to signs while staying grounded in real life (1:34:35) The consequences of ignoring the signs life gives us (1:41:45) Final thoughts and takeaways (1:45:55) Also mentioned in this episode: The Signs: The New Science of How to Trust Your Instincts - Dr. Tara’s new book  For more on Dr. Swart, follow her on Facebook, X/Twitter, Instagram, LinkedIn, or visit her Website. This episode is brought to you by Cozy Earth, LMNT, and Fatty15. Right now, get 40% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Lemonade Salt flavor is here to stay! Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru today. Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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