Dr Karan Explores

💬 All your GLP-1 weight loss questions answered in this AMA with Dr Karan. Should you take them if you’re not overweight? Can you stay on them forever? How can you eat better when your appetite is gone?
⚡ Answering the questions sent in by you, Dr Karan explains the science, benefits, risks and ethics of using drugs like Ozempic, Wegovy Mounjaro and Tirzepatide. 
🎧 Stay tuned to find out:
➡ Whether BMI matters when you’re thinking about going on GLP-1s
➡︎ If it’s safe to stay on GLP-1s forever - and how to come off safely
➡︎ Are maintenance doses and microdosing effective?
➡︎ How weight loss drugs affect the gut microbiome
➡︎ What to eat to hit fibre, protein and calorie targets when you have no appetite
➡︎ How hormones and women’s health conditions are impacted
➡︎ Why GLP-1s benefits extend way beyond weight loss
#DrKaran, #WeightLoss, #Ozempic, #Tirzepatide, #GutHealth, #GLP1, #AMA, #MedicalScience, #HealthEducation, #MythBusting
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 
📕 Chapters
(0:00) Introduction
(1:10) What is a GLP-1 agonist?
(2:00) Can fit people use Tirzepatide during a fat loss period to target visceral fat?
(3:58) What BMI do you need to have?
(5:22) Is everyone secretly on GLP-1s?
(6:03) Using GLP-1s for food noise, even if not overweight?
(8:00) Will the NHS soften the criteria for GLP-1s?
(8:55) Can you stay on GLP-1s forever?
(10:37) How to safely come off weight loss drugs
(12:03) Can you stop food noise once you come off the drugs?
(13:53) Are maintenance doses effective?
(14:57) Is microdosing GLP-1s an option?
(16:42) Short term vs long term side effects
(19:10) Is nausea a permanent side effect of weight loss drugs?
(20:16) Should you force yourself to eat?
(22:51) How to deal with “Ozempic face”
(24:13) Effect of GLP-1s on the gut microbiome
(26:32) How to eat enough while working out when you have no appetite?
(27:52) Can you build muscle on GLP-1s?
(29:56) Are hormones affected by GLP-1s?
(31:16) Can it help with endometriosis?
(32:53) Why LOAM can help while using GLP-1s
(34:29) Tips on high fibre, low calorie foods for GLP-1 users
(35:30) Inflammation, heart health - and other benefits of GLP-1s
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 
🤖 Discover my digital twin here: http://DrKaran.ai 
🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/   
Facebook: https://www.facebook.com/DrKaranR/  
TikTok: https://www.tiktok.com/@dr.karanr  
X: https://twitter.com/drkaranrajan  
Website: https://linktr.ee/ThisisVitalInformation

Most people are missing one of the most important nutrients for long-term health: fibre.In this solo episode, Dr Karan breaks down everything you need to know about fibre. From the cheapest ways to get more, to when you should eat it, and how it impacts your gut, cholesterol, metabolism, and long-term disease risk.What You’ll Learn:The cheapest high-fibre foods (and why beans dominate)When to eat fibre for maximum benefitHow fibre affects your gut microbiomeWhether fibre supplements are worth itHow much fibre you actually needWhy most people are under-consuming fibreThe science behind bloating and fibre adaptationHow fibre supports long-term health and disease preventionKey Insights from the Episode:“Your gut health and your microbiome health should not be compromised by your budget.”“If the goal is maximum fibre for the least amount of money, you're not going to find better than beans and legumes.”“The best time to take your fibre is basically whenever you remember to take your fibre.”“Only 5% of us are feeding our gut properly.”“I managed to reverse my high cholesterol… through increasing dietary fibre intake.”

About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai
📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#GutHealth #Fibre#Microbiome #HealthScience #Nutrition

💬 Exercise during pregnancy is surrounded by myths, fear, and outdated advice. But the truth is staying active can be one of the most powerful things you can do for both you and your baby.
⚡To unpack what safe, effective exercise really looks like during pregnancy and why misinformation is still so widespread - Dr Karan is joined by Dr Margie Davenport, professor and leading researcher in exercise during pregnancy. Whether you’re expecting, planning a pregnancy, or supporting someone who is, this conversation is essential listening.
🎧 Stay tuned to find out:
➡ Why there’s so much confusion and misinformation around exercise in pregnancy
➡︎ The science behind common myths about exercising while pregnant
➡︎ What “safe” exercise really looks like at each stage of pregnancy
➡︎ How physical activity benefits your baby’s health and development
➡︎ The role exercise plays in reducing the risk of serious complications
➡︎ Why outdated advice still persists in medical and public spaces
➡︎ How to approach exercise with confidence during pregnancy
#DrKaran, #PregnancyHealth, #PrenatalFitness, #ExerciseDuringPregnancy, #WomensHealth, #MedicalScience, #HealthEducation, #MythBusting
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 
📕 Chapters
(0:00) Introduction - The biggest myth regarding exercise and pregnancy
(1:00) Why exercise in pregnancy is surrounded by misinformation 
(2:05) What the evidence says 
(4:02) Exercise at different stages of pregnancy 
(6:00) The role of epigenetic factors
(7:55) How exercise during pregnancy impacts a child's long-term health 
(11:00) Exercise and gestational diabetes and preeclampsia
(12:03) How exercise affects labor outcomes
(13:50) Walking or aerobic exercise versus strength training
(16:50) The fear of miscarriage 
(18:57) Exercises pregnant women should definitely avoid 
(22:10) Weightlifting during pregnancy
(24:03) Taking creatine and supplements during pregnancy
(27:49) Optimal heart rate during pregnancy
(30:03) Exercise and high risk pregnancies
(33:02) How to conduct safe and ethical research in this area
(36:00) How to exercise safely postpartum 
(41:00) Exercise and the gut microbiome
(42:57) What Margie is researching next 
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 
🤖 Discover my digital twin here: http://DrKaran.ai 
🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/   
Facebook: https://www.facebook.com/DrKaranR/  
TikTok: https://www.tiktok.com/@dr.karanr  
X: https://twitter.com/drkaranrajan  
Website: https://linktr.ee/ThisisVitalInformation

Cooking isn’t just about flavour, it directly impacts your brain, gut, and heart health.

In this special episode, Dr Karan teams up with The Brain Docs, Drs. Ayesha & Dean Sherzai, to cook a nutrient-dense curry while breaking down the real science behind food and its impact on your body. From fibre and omega-3s to anti-inflammatory ingredients and the gut-brain connection.
Discussed in the episode:
 “the basic everyday food you eat literally makes your brain.”
 “what happens in your gut determines everything.”
This is not about “superfoods”, it’s about dietary patterns, real ingredients, and how what you eat daily shapes your long-term health.
 What You’ll Learn:

How food impacts brain function and mental health
Why fibre is critical for your gut and brain
The truth about tofu, coffee, and mushrooms
Why “anti-inflammatory diets” actually matter
The gut-brain connection explained simply
How cooking methods affect nutrition
Anti-inflammatory curry paste
Tofu (high-protein, low saturated fat)
Fibre-rich vegetables
Ginger, garlic, turmeric & spices
Cashew cream alternative to coconut milk

 What We Cook:

Anti-inflammatory curry paste
Tofu (high-protein, low saturated fat)
Fibre-rich vegetables
Ginger, garlic, turmeric & spices
Cashew cream alternative to coconut milk

Chapters:
00:00:30 – Intro
00:03:29 – “What happens in the gut determines everything”
00:04:24 – Tofu as the protein + the soy myth
00:06:51 – Coffee & cognition: What the data suggests
00:11:20 – Ginger for nausea & gut motility
00:12:36 – Dietary patterns over single foods (Mediterranean-style pattern explained)
00:16:55 – “Eat the rainbow”: Polyphenols, fibre types, carotenoids
00:19:29 – Omega-3 index & omega-3s as brain building blocks
00:20:19 – Omega-3 supplements: When it’s reasonable
00:22:23 – Prevention & the “pillars” analogy for long-term brain health
00:35:42 – Mental health & the gut: It’s multi-layered
00:36:24 – IBS: treating gut symptoms and mental health burden
00:48:01 – Turmeric for brain health & research background
00:49:20 – Turmeric supplements: Why high-dose curcumin is different from food
01:06:12 – “Taste and adjust”: The most important cooking step before serving
01:08:55 – Basil at the end & final flavour check
01:09:20 – Curry ready
01:12:50 – Dessert reveal: Chia pudding with cashews & mango
01:22:08 – Final thoughts

Endometriosis red flags are often missed, especially when symptoms look like IBS, bladder issues, or “normal” test results.In this episode of Dr Karan Explores, Dr Karan Rajan speaks with Carla Cressy about her lived experience of endometriosis, the long road to diagnosis, what severe disease can look like, and how to advocate for yourself when you’re being dismissed.In this conversation, we cover:Warning signs doctors often miss (bowel/rectal pain, bladder/UTI-like symptoms, bleeding after sex, severe fatigue)Why endometriosis can be mislabelled as IBS/IBDWhy normal blood tests/scans don’t necessarily rule endometriosis out — and what to do nextThe impact on mental health, work, relationships, and quality of lifeFertility and access: egg freezing, NHS gaps, and why pathways matterPractical advocacy: symptom diaries, bringing someone to appointments, asking for documentation, and next-step questions to move care forwardAbout Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai 📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com