Kieran Reynolds talks to Yun Jung Kim, Senior Specialist Pharmacist in Hepatology about primary biliary cholangitis (PBC). Discussion includes what PBC is, symptoms (and symptom control), diagnosis, treatment and how pharmacy professionals can contribute to the management of patients with PBC.
Yun Jung Kim - Senior Specialist Pharmacist in Hepatology University Hospital Southampton NHS Foundation Trust and Vice-Chair, BHPG
Kieran Reynolds - Advanced Specialist Pharmacist (Medicines Governance), SPS
Useful links:
The British Liver Trust’s information on primary biliary cholangitis
https://britishlivertrust.org.uk/information-and-support/liver-conditions/primary-biliary-cholangitis/
The British Liver Trust’s information on diagnosing primary biliary cholangitis
https://britishlivertrust.org.uk/information-and-support/liver-conditions/primary-biliary-cholangitis/diagnosis/
The British Liver Trust’s information on treating primary biliary cholangitis
https://britishlivertrust.org.uk/information-and-support/liver-conditions/primary-biliary-cholangitis/diagnosis/
PBC Foundation website
https://www.pbcfoundation.international/
The British Society of Gastroenterology primary biliary cholangitis (PBC) care bundle
https://www.bsg.org.uk/clinical-resource/primary-biliary-cholangitis-(pbc)-care-bundle
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Autoimmune hepatitis (AIH)
Kieran Reynolds talks to Sonal Patel, Lead Hepatology Pharmacist about autoimmune hepatitis (AIH). Discussion includes what AIH is, prevalence, diagnosis, treatment and how pharmacy professionals can contribute to the management of patients with AIH.
Sonal Patel - Lead Hepatology Pharmacist, Guy’s and St. Thomas’ Trust and Chief Pharmaceutical Officer’s Clinical Fellow 2024/25 at the General Pharmaceutical Council (GPhC)
Kieran Reynolds - Advanced Specialist Pharmacist (Medicines Governance), SPS
Useful links:
SPS article on assessing liver function and interpreting liver blood tests
https://www.sps.nhs.uk/articles/assessing-liver-function-and-interpreting-liver-blood-tests/
NHS website information on prednisolone
https://www.nhs.uk/medicines/prednisolone/
NHS website information on budesonide
https://www.nhs.uk/medicines/budesonide-tablets-capsules-and-granules/about-budesonide-tablets-capsules-and-granules/
NHS website information on azathioprine
https://www.nhs.uk/medicines/azathioprine/
The Society of Endocrinology information on adrenal crisis
https://www.endocrinology.org/clinical-practice/clinical-guidance/adrenal-crisis/
SPS Medicines Monitoring tool
https://www.sps.nhs.uk/home/tools/drug-monitoring/
The Green Book: information on vaccines for vaccine preventable diseases
https://www.gov.uk/government/collections/immunisation-against-infectious-disease-the-green-book#the-green-book
AIH support website
https://aihsupport.org.uk/
The British Liver Trust’s information on autoimmune hepatitis
https://britishlivertrust.org.uk/information-and-support/liver-conditions/autoimmune-hepatitis/
Kieran Reynolds talks to Arron Jones, Lead Hepatology Pharmacist about metabolic dysfunction associated steatotic liver disease (MASLD). Discussion includes what MASLD/MASH stands for, prevalence, diagnosis, treatment; including advice to give to patients accessing GLP-1 RAs online, and emerging therapies.
Arron Jones - Lead Hepatology Pharmacist, Bart’s Health Trust
Kieran Reynolds - Advanced Specialist Pharmacist (Medicines Governance), SPS
Useful links:
The British Liver Trust’s information on MASLD, NAFLD and fatty liver disease
https://britishlivertrust.org.uk/information-and-support/liver-conditions/masld-nafld-and-fatty-liver-disease/
The NHS Eatwell Guide
https://www.nhs.uk/live-well/eat-well/food-guidelines-and-food-labels/the-eatwell-guide/
The South Asian Eatwell Guide
https://mynutriweb.com/the-south-asian-eatwell-guide/
SPS article on using statins in liver impairment
https://www.sps.nhs.uk/articles/using-statins-in-liver-impairment/
The General Pharmaceutical Council’s FAQs on weight loss medications (including a guide for patients on how to keep safe when getting medicines or treatment online: scroll to bottom of page to access)
https://www.pharmacyregulation.org/patients-and-public/standards-you-can-expect-using-pharmacy-services/weight-loss-medications-faq
Sheetal Ladva, Senior Medicines Advice Pharmacist at SPS, presents a summary of the resources published by SPS between 21st and 27th June. To easily find a list of newly published pages go to sps.nhs.uk, select ‘search’, click in the search bar, and press enter.
Quick links to highlighted resources:
Safe handling of monoclonal antibodies
Considerations for occupational safety when preparing monoclonal antibodies (mAb)
https://www.sps.nhs.uk/articles/safe-handling-of-monoclonal-antibodies/
Tranexamic acid injection for treatment of severe haemorrhage
SPS PGD template for administering tranexamic acid injection for treatment of severe haemorrhage by registered Paramedics and Nurses
https://www.sps.nhs.uk/articles/tranexamic-acid-injection-for-treatment-of-severe-haemorrhage/
June edition of Spotlight
A digest of NHS Specialist Pharmacy Service support for professionals working in all areas of the healthcare system for June 2025
https://www.sps.nhs.uk/articles/spotlight-june-2025/
Next events – forthcoming webinars and conferences
https://www.sps.nhs.uk/home/events/next-events/
Podcast description:
NHS Specialist Pharmacy Service serves healthcare professionals across the NHS who are involved in all aspects of buying, making and using medicines. Our motto is 'do once and share'.
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24 June: Intrathecal administration, fidaxomicin and vancomycin, & job opportunities at SPS
24th June: Intrathecal administration, fidaxomicin & vancomycin, & job opportunities at SPS
Sheetal Ladva, Senior Medicines Advice Pharmacist at SPS, presents a summary of the resources published by SPS between 14th and 20th June.
To easily find a list of newly published pages go to sps.nhs.uk, select ‘search’, click in the search bar, and press enter.
Quick links to highlighted resources:
Job vacancy
SPS Medicines Advice Pharmacist
https://careers.liverpoolft.nhs.uk/current-vacancies/#!/job/v7226351
Understanding risks with intrathecal administration
The intrathecal route is a high-risk route of administration. Incorrect administration of medicines unsafe for this route can result in patient death.
https://www.sps.nhs.uk/articles/understanding-risks-with-intrathecal-administration/
Choosing between fidaxomicin options
Organisations should choose suitable fidaxomicin formulary options and mitigate risks. Several factors affect decision making.
https://www.sps.nhs.uk/articles/choosing-between-fidaxomicin-options/
Choosing between vancomycin options
Organisations should choose suitable formulary options for oral vancomycin and mitigate risks. Several factors affect decision making.
https://www.sps.nhs.uk/articles/choosing-between-oral-vancomycin-options/
Time Critical Medicines Quality Improvement Collaborative
We invite NHS Trusts to express an interest in joining this quality improvement collaborative
https://www.sps.nhs.uk/articles/time-critical-medicines-quality-improvement-collaborative/
Next events – forthcoming webinars and conferences
https://www.sps.nhs.uk/home/events/next-events/
Podcast description:
NHS Specialist Pharmacy Service serves healthcare professionals across the NHS who are involved in all aspects of buying, making and using medicines. Our motto is 'do once and share'.
NHS Specialist Pharmacy Service serves healthcare professionals across the NHS who are involved in all aspects of buying, making and using medicines. Our motto is 'do once and share'.
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